1333109-36-6

Basic information

• Product Name: N-(4-isopropoxy-3-methoxybenzyl)-4-isopropoxy-3-methoxybenzamide
• Synonyms: N-(4-isopropoxy-3-methoxybenzyl)-4-isopropoxy-3-methoxybenzamide
• CAS NO: 1333109-36-6
• Molecular Weight: 387.476
• Mol File: 1333109-36-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-(4-isopropoxy-3-methoxybenzyl)-4-isopropoxy-3-methoxybenzamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(4-isopropoxy-3-methoxybenzyl)-4-isopropoxy-3-methoxybenzamide(1333109-36-6)
• EPA Substance Registry System: N-(4-isopropoxy-3-methoxybenzyl)-4-isopropoxy-3-methoxybenzamide(1333109-36-6)

Safety Data

• Hazardous Substances Data: 1333109-36-6(Hazardous Substances Data)

Upstream product

• 121-33-5 vanillin 
• 2538-98-9 4-isopropyloxy-3-methoxybenzaldehyde 
• 3535-33-9 4-isopropyloxy-3-methoxybenzoic acid 
• 98799-37-2 (4-isopropoxy-3-methoxyphenyl)methanamine 
• 121-34-6 3-methoxy-4-hydroxybenzoic acid 
• 98799-36-1 4-isopropoxy-3-methoxybenzaldehyde oxime 

Downstream Products

• 1333109-38-8 tert-butyl (1,2-bis(4-isopropoxy-3-methoxyphenyl)-2-oxoethyl)carbamate 
• 1333109-40-2 2-amino-1,2-bis(4-isopropoxy-3-methoxyphenyl)ethanone trifluoroacetate 
• 1333109-43-5 N-(1,2-bis(4-isopropoxy-3-methoxyphenyl)-2-oxoethyl)-1-benzyl-6-(benzyloxy)-5-methoxy-1H-indole-2-carboxamide 
• 1333109-60-6 9-benzyl-7-(benzyloxy)-3,4-bis(4-isopropoxy-3-methoxyphenyl)-6-methoxy-2H-pyrido[3,4-b]indol-1(9H)-one 
• 1333109-66-2 9-benzyl-7-hydroxy-3,4-bis(4-hydroxy-3-methoxyphenyl)-6-methoxy-2H-pyrido[3,4-b]indol-1(9H)-one 
• 1333109-63-9 7-hydroxy-3,4-bis(4-hydroxy-3-methoxyphenyl)-6-methoxy-2H-pyrido[3,4-b]indol-1(9H)-one 
• 1333109-44-6 N-(1,2-bis(4-isopropoxy-3-methoxyphenyl)-2-oxoethyl)-1-benzyl-5-(benzyloxy)-6-methoxy-1H-indole-2-carboxamide 
• 1333109-61-7 9-benzyl-6-(benzyloxy)-3,4-bis(4-isopropoxy-3-methoxyphenyl)-7-methoxy-2H-pyrido[3,4-b]indol-1(9H)-one 
• 1333109-64-0 6-hydroxy-3,4-bis(4-hydroxy-3-methoxyphenyl)-7-methoxy-2H-pyrido[3,4-b]indol-1(9H)-one 
• 1333109-45-7 N-(1,2-bis(4-isopropoxy-3-methoxyphenyl)-2-oxoethyl)-1-methyl-1H-indole-2-carboxamide 
• 1333109-62-8 3,4-bis(4-isopropoxy-3-methoxyphenyl)-9-methyl-2H-pyrido[3,4-b]indol-1(9H)-one 
• 1333109-65-1 3,4-bis(4-hydroxy-3-methoxyphenyl)-9-methyl-2H-pyrido[3,4-b]indol-1(9H)-one 
• 1333109-37-7 (4-isopropoxy-3-methoxybenzoyl)(4-isopropoxy-3-methoxybenzyl)carbamic acid tert-butyl ester 

Relevant articles and documents

Synthesis and topoisomerase i inhibitory activity of a novel diazaindeno[2,1-b]phenanthrene analogue of Lamellarin D

A novel 5-oxa-6a,8-diazaindeno[2,1-b]phenanthren-7-one scaffold was designed and synthesized as an active analogue of the cytotoxic marine alkaloid Lamellarin D. The design was based on molecular modeling of the site of interaction of Lamellarin D with DNA-topoisomerase I cleavable complex, whereas the synthesis capitalized on a simple Friedel-Crafts cyclization of indole to a β-carbolinone nucleus. The product exhibited topoisomerase I poisoning activity and submicromolar cytotoxicity on human non-small cell lung cancer H460 cell line.