98799-36-1

Basic information

• Product Name: 4-ISOPROPOXY-3-METHOXY-BENZALDEHYDE OXIME
• Synonyms: 3-methoxy-4-isopropoxybenzoxime;n-{[3-methoxy-4-(propan-2-yloxy)phenyl]methylidene}hydroxylamine
• CAS NO: 98799-36-1
• Molecular Formula: C₁₁H₁₅NO₃
• Molecular Weight: 209.25
• Mol File: 98799-36-1.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 307.4°Cat760mmHg
• Flash Point: 139.7°C
• Appearance: /
• Density: 1.08g/cm³
• Vapor Pressure: 0.000316mmHg at 25°C
• Refractive Index: 1.498
• CAS DataBase Reference: 4-ISOPROPOXY-3-METHOXY-BENZALDEHYDE OXIME(CAS DataBase Reference)
• NIST Chemistry Reference: 4-ISOPROPOXY-3-METHOXY-BENZALDEHYDE OXIME(98799-36-1)
• EPA Substance Registry System: 4-ISOPROPOXY-3-METHOXY-BENZALDEHYDE OXIME(98799-36-1)

Safety Data

• Hazardous Substances Data: 98799-36-1(Hazardous Substances Data)

Usage

InChI:InChI=1/C11H15NO3/c1-8(2)15-10-5-4-9(7-12-13)6-11(10)14-3/h4-8,13H,1-3H3/b12-7-

Upstream product

• 121-33-5 vanillin 
• 2538-98-9 4-isopropyloxy-3-methoxybenzaldehyde 

Downstream Products

• 854185-11-8 4-isopropoxy-3-methoxyphenylmethanamine hydrochloride 
• 1333109-36-6 N-(4-isopropoxy-3-methoxybenzyl)-4-isopropoxy-3-methoxybenzamide 
• 1333109-37-7 (4-isopropoxy-3-methoxybenzoyl)(4-isopropoxy-3-methoxybenzyl)carbamic acid tert-butyl ester 
• 98799-37-2 (4-isopropoxy-3-methoxyphenyl)methanamine 
• 98799-39-4 2-iodo-5-methoxy-4-isopropoxy-N-acetylbenzylamine 
• 98799-38-3 3-methoxy-4-isopropoxy-N-acetylbenzylamine 
• 98799-40-7 2-iodo-5-methoxy-4-isopropoxybenzylamine 

Relevant articles and documents

Synthesis and topoisomerase i inhibitory activity of a novel diazaindeno[2,1-b]phenanthrene analogue of Lamellarin D

A novel 5-oxa-6a,8-diazaindeno[2,1-b]phenanthren-7-one scaffold was designed and synthesized as an active analogue of the cytotoxic marine alkaloid Lamellarin D. The design was based on molecular modeling of the site of interaction of Lamellarin D with DNA-topoisomerase I cleavable complex, whereas the synthesis capitalized on a simple Friedel-Crafts cyclization of indole to a β-carbolinone nucleus. The product exhibited topoisomerase I poisoning activity and submicromolar cytotoxicity on human non-small cell lung cancer H460 cell line.

Direct Synthesis of Benzophenanthridines and Benzophenanthridones via SRN1 Reactions

A straightforward and high-yield route to the 11,12-dihydrobenzophenanthridine (3) and 11,12-dihydrobenzophenanthridone (14) ring systems is based upon an SRN1 reaction between 2-halobenzylamines 1 or 2-halobenzoic acids 11 and enolates derived from tetralones 2.The efficient dehydrogenation of 3 or 14 gives the benzophenthridines 4 or benzophenanthridones 15.Use of properly substituted reactants leads to nitidine, avicine, and fagaronine and to analogues of those natural products.