1333112-03-0

Basic information

• Product Name: (E)-3-methyl-4-[4-methyl-2-thioxo-3-p-tolyl-2,3-dihydro-1,3-oxazin-6-ylidene]-1-phenyl-1H-pyrazol-5(4H)-one
• Synonyms: (E)-3-methyl-4-[4-methyl-2-thioxo-3-p-tolyl-2,3-dihydro-1,3-oxazin-6-ylidene]-1-phenyl-1H-pyrazol-5(4H)-one
• CAS NO: 1333112-03-0
• Molecular Weight: 389.478
• Mol File: 1333112-03-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (E)-3-methyl-4-[4-methyl-2-thioxo-3-p-tolyl-2,3-dihydro-1,3-oxazin-6-ylidene]-1-phenyl-1H-pyrazol-5(4H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-3-methyl-4-[4-methyl-2-thioxo-3-p-tolyl-2,3-dihydro-1,3-oxazin-6-ylidene]-1-phenyl-1H-pyrazol-5(4H)-one(1333112-03-0)
• EPA Substance Registry System: (E)-3-methyl-4-[4-methyl-2-thioxo-3-p-tolyl-2,3-dihydro-1,3-oxazin-6-ylidene]-1-phenyl-1H-pyrazol-5(4H)-one(1333112-03-0)

Safety Data

• Hazardous Substances Data: 1333112-03-0(Hazardous Substances Data)

Upstream product

• 100-63-0 phenylhydrazine 
• 771-03-9 3-acetyl-4-hydroxy-6-methyl-2H-pyran-2-one 
• 463-71-8 thiophosgene 
• 1029478-29-2 C₂₁H₂₁N₃O₂ 

Relevant articles and documents

N-substituted [phenyl-pyrazolo]-oxazin-2-thiones as COX-LOX inhibitors: Influence of the replacement of the oxo -group with thioxo- group on the COX inhibition activity of N-substituted pyrazolo-oxazin-2-ones

Targeting to the synthesis of potent dual acting COX/LOX inhibitors as future anti-inflammatory drugs, we attempted a modification of the compounds based on docking analysis results. A substitution of the oxygen of the oxo-group of the oxazin-2-one ring b