1333113-84-0Relevant academic research and scientific papers
New Heterocyclic Product Space for the Castagnoli-Cushman Three-Component Reaction
Dar'In, Dmitry,Bakulina, Olga,Chizhova, Maria,Krasavin, Mikhail
, p. 3930 - 3933 (2015)
Significant expansion of heterocyclic product space accessible by the Castagnoli-Cushman reaction (CCR) has been achieved via the use of glutaric anhydride analogues containing endocyclic substitutions with oxygen, nitrogen, and sulfur. Incorporation of these heteroatoms in the anhydride's backbone results in enhanced reactivity and generally lower temperatures that are required for the reactions to go to completion. These findings are particularly significant in light of the CCR recently recognized as an efficient tool for lead-oriented synthesis.
Improved performance by replacing iminodiacetic residues with glyceryl residues in symmetrically branched oligoglycerols
Nemoto, Hisao,Ishihara, Atsushi,Araki, Takaaki,Katagiri, Ayato,Kamiya, Masaki,Matsushita, Tsuyoshi,Hattori, Hatsuhiko,Mimura, Yukiteru,Tomoda, Yutaka,Yamasaki, Motoo
supporting information; experimental part, p. 4724 - 4727 (2011/09/20)
Synthesis of a symmetrically branched diglycerol (BGL002, involving one iminodiacetic residue) as a G2 dendron, and the tetradecaglycerol (BGL014, involving one iminodiacetic residue) as a G4 dendron, is described. Several members of the BGL family of G2-
