1333152-18-3

Basic information

• Product Name: (Z)-1-(3,3-difluoroazetidin-1-yl)-3-(3-(3-methoxy-5-(trifluoromethyl)phenyl)-1H-1,2,4-triazol-1-yl)prop-2-en-1-one
• Synonyms: (Z)-1-(3,3-difluoroazetidin-1-yl)-3-(3-(3-methoxy-5-(trifluoromethyl)phenyl)-1H-1,2,4-triazol-1-yl)prop-2-en-1-one
• CAS NO: 1333152-18-3
• Molecular Weight: 388.297
• Mol File: 1333152-18-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (Z)-1-(3,3-difluoroazetidin-1-yl)-3-(3-(3-methoxy-5-(trifluoromethyl)phenyl)-1H-1,2,4-triazol-1-yl)prop-2-en-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: (Z)-1-(3,3-difluoroazetidin-1-yl)-3-(3-(3-methoxy-5-(trifluoromethyl)phenyl)-1H-1,2,4-triazol-1-yl)prop-2-en-1-one(1333152-18-3)
• EPA Substance Registry System: (Z)-1-(3,3-difluoroazetidin-1-yl)-3-(3-(3-methoxy-5-(trifluoromethyl)phenyl)-1H-1,2,4-triazol-1-yl)prop-2-en-1-one(1333152-18-3)

Safety Data

• Hazardous Substances Data: 1333152-18-3(Hazardous Substances Data)

Upstream product

• 288315-03-7 3,3-difluoroazetidine hydrochloride 
• 1333154-08-7 (Z)-3-(3-(3-methoxy-5-(trifluoromethyl)phenyl)-1H-1,2,4-triazol-1-yl)acrylic acid 
• 868167-61-7 3-methoxy-5-(trifluoromethyl)benzonitrile 
• 1251940-10-9 C₉H₈F₃NOS 
• 1333153-09-5 C₁₀H₁₀F₃NOS 
• 1333153-10-8 3-(3-methoxy-5-(trifluoromethyl)phenyl)-1H-1,2,4-triazole 
• 1333151-73-7 propan-2-yl (Z)-3-[3-[3-methoxy-5-(trifluoromethyl)phenyl]-1,2,4-triazol-1-yl]prop-2-enoate 

Relevant articles and documents

NUCLEAR TRANSPORT MODULATIORS AND USES THEREOF

The invention generally relates to the field of nuclear transport modulators, e.g., CRM1 inhibitors, and more particularly to new substituted-heterocyclic azole compounds, the synthesis and use of these compounds and their pharmaceutical compositions, e.g