13332-71-3

Usage

InChI:InChI=1/C8H9NO2/c1-5-6(4-9)7(10)11-8(5,2)3/h1-3H3

Upstream product

• 115-22-0 3-Hydroxy-3-methyl-2-butanone 
• 105-56-6 ethyl 2-cyanoacetate 
• 189102-39-4 3-(tert-butyldimethylsilyloxy)-3-methylbutan-2-one 
• 1292797-55-7 2-(3-(tert-butyldimethylsilyloxy)-3-methylbutan-2-ylidene)propanedinitrile 
• 364599-35-9 2-imino-4,5,5-trimethyl-2,5-dihydrofuran-3-carbonitrile 
• 621-03-4 cyanoacetanilide 

Downstream Products

• 1315573-87-5 N-{2-[(aminocarbonyl)hydrazono]-1,1-dimethylpropyl}-4,6,6-trimethyl-2-oxo-5,6-dihydro-2H-pyran-3-carboxamide 
• 1417819-39-6 4-((R)-1-phenylethylamino)-1,1-dimethylfuro[3,4-c]pyridin-3(1H)-one 
• 1417819-41-0 4-((S)-1-phenylethylamino)-1,1-dimethylfuro[3,4-c]pyridin-3(1H)-one 
• 1417819-49-8 4-((S)-1-cyclohexylethylamino)-1,1-dimethylfuro[3,4-c]pyridin-3(1H)-one 
• 1417819-52-3 C₁₇H₁₈N₂O₂ 
• 1417819-01-2 4-(benzylamino)-1,1-dimethylfuro[3,4-c]pyridin-3(1H)-one 
• 1417819-09-0 4-(2-(piperazin-1-yl)ethylamino)-1,1-dimethylfuro[3,4-c]pyridine-3(1H)-one 
• 285991-71-1 4-chloro-1,1-dimethylfuro[3,4-c]pyridine-3(1H)-one 
• 1580537-72-9 4-[3-(4-chlorophenoxy)-2-hydroxy-propylamino]-1,1-dimethyl-1H-furo[3,4-c]pyridin-3-one 
• 1580537-66-1 4-[3-(4-fluorophenoxy)-2-hydroxy-propylamino]-1,1-dimethyl-1H-furo[3,4-c]pyridin-3-one 
• 1580537-64-9 (2-hydroxy-3-p-tolyloxypropylamino)-1,1-dimethyl-1H-furo[3,4-c]pyridin-3-one 
• 1580537-59-2 4-(2-hydroxy-3-phenoxypropylamino)-1,1-dimethyl-1H-furo[3,4-c]pyridin-3-one 
• 1580537-56-9 4-(1,1-dimethyl-3-oxo-1,3-dihydrofuro[3,4-c]pyridin-4-ylamino)benzenesulfonamide 
• 1580537-51-4 4-(4-chlorophenylamino)-1,1-dimethyl-1H-furo[3,4-c]pyridin-3-one 

Relevant academic research and scientific papers

Modification of nonlinear optical dyes for dye sensitized solar cells: A new use for a familiar acceptor

The chemistry of electron deficient π-acceptors offers unique challenges in the rational design and synthesis of organic dyes for use in solar cells. We have synthesized 2-cyano-2-(3-cyano-4-((E)-4-(dibutylamino)styryl)-5,5- dimethylfuran-2(5H)-ylidene)et

A convenient synthesis of substituted 3-pyrrolin-2-ones from α-cetols

A simple and efficient method for the preparation of the title compounds is described from cyanoacetamides and 3-hydroxy-3-methyl-2-butanone in the presence of sodium ethylate at room temperature. The 3-carboxamido-N-alkyl-4,5,5-trimethyl-5-dihydro-2H-pyrrol-2-ones lead to unsaturated derivatives by condensation with aldehydes, while hydrogenation give rise to the corresponding pyrrolidin-2-ones.

Rapid and efficient synthesis of 2-[3-cyano-4-(2-aryliden)-5,5-dimethyl-5H-furan-2-ylidene]-malononitrile under focused microwave irradiation

New biological potential furan-2-ylidenemalononitriles (IIIa-j) were synthetised efficiently by one-pot condensation under focused microwave from starting and easy available compounds.

Tuning the solid-state emission of small push-pull dipolar dyes to the far-red through variation of the electron-acceptor group

Series of solid-state emitters based on the D-π-A dipolar structure and featuring various electron-donor and electron-acceptor groups were designed, and their spectroscopic properties studied. From weak emission in dilute solutions, intense emissions in aggregated state (AIE) and in the crystalline state were obtained. Analysis in light of crystal structures obtained by X-ray diffraction revealed specific crystal packing and presence of long chain of emitting aggregates. This simple molecular engineering around the D-π-A dipolar structure provides easy access to a wide range of effective solid-state emitters allowing modulation of emission wavelengths up to the near infrared (λem reaching 735 and 768 nm for compound 2f and 3f bearing the strongest electron-withdrawing group).

A serendipitous conversion of enaminolactone nitriles with primary amines: A new synthesis of substituted 2-aminopyridine derivatives

In the course of our studies on Cerpegin analogues synthesis, a serendipitous reactivity of enaminolactone nitrile has been observed. Instead of expecting iminocerpegins, we have gained new class of substituted 2-aminopyridines. The methodology has been applied on a wide range of primary amines, as aliphatic, aromatic, heteroaromatic and also, diamines, hydrazines and chiral amines.

A rapid and efficient one-pot synthesis of substituted 2-(5 H)-furanones under focused microwave irradiations

3-Hydroxy-3-methyl-2-butanone 1 reacted with ethyl cyanocetate in 2 in the presence of sodium ethoxide under focused microwave irradiations to afford 3-cyano-4,5,5-trimethyl-2-(5H)-furanone 3. Furanone 3 then condensed with aromatic or heteroaromatic aldehydes 4a-h to produce 3-cyano-4-(trans- aryl-vinyl)-5,5-dimethyl-2-(5H)-furanones 5a-h in high overall yields (71- 88%).