1333203-95-4Relevant articles and documents
A Versatile Organocatalytic Approach for the Synthesis of Enantioenriched gem-Difluorinated Compounds
Saulnier, Steve,Ciardi, Moira,Lopez-Carrillo, Veronica,Gualandi, Andrea,Cozzi, Pier Giorgio
, p. 13689 - 13695 (2015/09/22)
The combination of a practical and highly enantioselective organocatalytic reaction, which allows the stereoselective introduction of a benzodithiol group, with a fluorination step, gives a new and effective strategy for the stereoselective synthesis of difluorinated building blocks. The benzodithiol group is a versatile and chameleonic group that can be further functionalized before fluorination, giving customized and tailored useful synthetic strategies. As an example of the application of this facile strategy, the effective enantioselective synthesis of difluoroarundic acid is described. All you need is fluor! The combination of a practical and highly enantioselective organocatalytic reaction with a fluorination step provides a new and effective strategy for the stereoselective synthesis of enantioenriched difluorinated building blocks (see scheme).
A highly stereoselective organocatalytic approach to Lilial and muguesia
Gualandi, Andrea,Emma, Marcogiuseppe,Giacoboni, Jessica,Mengozzi, Luca,Cozzi, Piergiorgio
supporting information, p. 449 - 452 (2013/04/10)
The stereoselective alkylation of aldehydes with benzodithiolylium tetrafluoborate gave a straightforward access to key compounds for the synthesis of fragrances and flavors. Georg Thieme Verlag Stuttgart · New York.