1333234-65-3Relevant academic research and scientific papers
Synthesis of aminopropylamino derivatives of betulinic and oleanolic acids
Giniyatullina,Kazakova,Medvedeva,Sorokina,Zhukova,Tolstikova,Tolstikov
, p. 329 - 337 (2013)
Triterpenoids with the following amine fragments in C3 and C28 positions were synthesized on the basis of betulinic and oleanolic acids: (3-aminopropoxy)-, 3-acetyl-(3-aminopropyl)amino-, 6-[bis(3-aminopropyl)amino] hexylamino-, and (3-aminopropyl)-4-aminophenylsulfonyl-4-phenylamino. Amide of betulonic acid with 4,4′-diaminodiphenylsulfonic substituent was shown to exhibit no antitumor effect, but to have a pronounced anti-inflammatory activity.
