1333236-95-5Relevant academic research and scientific papers
Total synthesis of umuravumbolide and hyptolide through silicon-tethered ring-closing metathesis
Chowdhury, Partha Sarathi,Kumar, Pradeep
, p. 4586 - 4593 (2013)
The total synthesis of umuravumbolide and hyptolide has been achieved in a efficient manner by using temporary silicon-tethered ring-closing metathesis and cross-coupling reactions as key steps. The stereogenic centres were generated by means of proline-catalysed α-aminoxylation of aldehydes and Brown's asymmetric allylation method. An efficient total synthesis of umuravumbolide and hyptolide has been achieved by using temporary silicon-tethered ring-closing metathesis. The stereogenic centres were generated by using asymmetric allyl boration and proline-catalysed α-aminoxylation with high degrees of enantioselectivity. Copyright
Synthesis of undecachlorosulfolipid A: Re-evaluation of the nominal structure
Nilewski, Christian,Deprez, Nicholas R.,Fessard, Thomas C.,Li, Dong Bo,Geisser, Roger W.,Carreira, Erick M.
, p. 7940 - 7943 (2011/10/08)
Halo-giant: The title compound at the left in the scheme was constructed by the synthesis and coupling of two stereochemically challenging fragments. A comparison of the NMR data of the synthetic material and the natural product indicates that the configuration had been misassigned in the latter. PT=5-(1-phenyltetrazolyl).
