1333241-35-2

Upstream product

• 614-75-5 2-Hydroxyphenylacetic acid 
• 220801-66-1 5-bromo-2-hydroxylphenylacetic acid methyl ester 
• 1333225-28-7 methyl 2-(5-bromo-2-((tert-butyldimethylsilyl)oxy)-phenyl)acetate 
• 1333225-29-8 methyl 2-(5-bromo-2-(tert-butyldimethylsilyloxy)phenyl)-3-(4-fluorophenyl)-3-oxopropanoate 
• 1333225-30-1 methyl 2-(5-bromo-2-hydroxyphenyl)-3-(4-fluorophenyl)-3-oxopropanoate 
• 1333225-31-2 methyl 5-bromo-2-(4-fluorophenyl)benzofuran-3-carboxylate 
• 1333225-32-3 methyl 5-bromo-2-(4-fluorophenyl)-6-nitrobenzofuran-3-carboxylate 
• 1333225-33-4 methyl 6-amino-5-bromo-2-(4-fluorophenyl)benzofuran-3-carboxylate 
• 1333225-34-5 methyl 5-bromo-2-(4-fluorophenyl)-6-(methanesulfonamido)benzofuran-3-carboxylate 
• 1333225-35-6 methyl 5-bromo-2-(4-fluorophenyl)-6-(N-methylmethylsulfonamido)benzofuran-3-carboxylate 
• 1333225-19-6 5-bromo-2-(4-fluorophenyl)-6-(N-methylmethylsulfonamido)-1-benzofuran-3-carboxylic acid 
• 1029054-27-0 2-[3-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-phenyl]-oxazolo[4,5-b]pyridine 
• 1333225-20-9 5-bromo-2-(4-fluorophenyl)-N-methyl-6-(N-methylmethylsulfonamido)benzo furan-3-carboxamide 

Relevant academic research and scientific papers

HETEROCYCLIC-SUBSTITUTED BENZOFURAN DERIVATIVES AND METHODS OF USE THEREOF FOR THE TREATMENT OF VIRAL DISEASES

The present invention relates to compounds of formula (I) that are useful as hepatitis C virus (HCV) NS5B polymerase inhibitors, the synthesis of such compounds, and the use of such compounds for inhibiting HCV NS5B polymerase activity, for treating or preventing HCV infections and for inhibiting HCV viral replication and/or viral production in a cell-based system.

HETEROCYCLIC-SUBSTITUED BENZOFURAN DERIVATIVES AND METHODS OF USE THEREOF FOR THE TREATMENT OF VIRAL DISEASES

The present invention relates to compounds of formula (1) that are useful as hepatitis C virus (HCV) NS5B polymerase inhibitors, the synthesis of such compounds, and the use of such compounds for inhibiting HCV NS5B polymerase activity, for treating or preventing HCV infections and for inhibiting HCV viral replication and/or viral production in a cell-based system.

INHIBITORS OF HEPATITIS C VIRUS NS5B POLYMERASE

Compounds of formula (I) that are used as hepatitis C virus (HCV) NS5B polymerase inhibitors, the synthesis of such compounds, and the use of such compounds for inhibiting HCV NS5B polymerase activity, for treating or preventing HCV infections and for inhibiting HCV viral replication and /or viral production in a cell-based system. Wherein Z, R30, R40, R50 and R60 of compounds of formula (I) are herein defined as in the description.

INHIBITORS OF HEPATITIS C VIRUS NS5B POLYMERASE

Disclosed are compounds of formula (I) that are used as hepatitis C virus (HCV) NS5B polymerase inhibitors, the synthesis of such compounds, and the use of such compounds for inhibiting HCV NS5B polymerase activity, for treating or preventing HCV infectio