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614-75-5

614-75-5

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614-75-5 Usage

Chemical Properties

Off-White Solid

Uses

2-Hydroxyphenylacetic Acid is an intermediate in the synthesis of atenolol and 3,4-dihydroxyphenylacetic acid.

Definition

ChEBI: A hydroxy monocarboxylic acid that is acetic acid in which one of the methyl hydrogens is substituted by a 2-hydroxyphenyl group. It is a metabolite of phenylalanine and is excreted in the urine of patients suffering from diseases like phenylketonuria.

Purification Methods

Crystallise the acid from ether or chloroform (m 147o, m from latter solvent is always lower). [Beilstein 10 H 187, 10 I 81, 10 II 112, 10 III 422, 10 IV 536.]

Check Digit Verification of cas no

The CAS Registry Mumber 614-75-5 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 6,1 and 4 respectively; the second part has 2 digits, 7 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 614-75:
(5*6)+(4*1)+(3*4)+(2*7)+(1*5)=65
65 % 10 = 5
So 614-75-5 is a valid CAS Registry Number.
InChI:InChI=1/C8H8O3/c9-7-4-2-1-3-6(7)5-8(10)11/h1-4,9H,5H2,(H,10,11)/p-1

614-75-5 Well-known Company Product Price

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  • (Code)Product description
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  • Alfa Aesar

  • (A13924)  2-Hydroxyphenylacetic acid, 98%   

  • 614-75-5

  • 10g

  • 246.0CNY

  • Detail

  • Alfa Aesar

  • (A13924)  2-Hydroxyphenylacetic acid, 98%   

  • 614-75-5

  • 50g

  • 1102.0CNY

  • Detail

614-75-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name (2-hydroxyphenyl)acetic acid

1.2 Other means of identification

Product number -
Other names Benzeneacetic acid, 2-hydroxy-

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:614-75-5 SDS

614-75-5Relevant articles and documents

Faulkner et al.

, p. 1741 (1968)

Synthetic method of benzofuranone

-

, (2020/06/16)

The invention provides a synthetic method of benzofuranone. According to the method, o-cresol which is relatively easy to obtain is used as an initial raw material, and the target product benzofuranone is prepared through four-step reaction; and the whole preparation process is mild in condition, high in yield, easy to operate, small in environmental pollution and suitable for large-scale industrial production.

Synthesis and biological evaluation of 3-arylcoumarin derivatives as potential anti-diabetic agents

Hu, Yuheng,Wang, Bing,Yang, Jie,Liu, Teng,Sun, Jie,Wang, Xiaojing

, p. 15 - 30 (2018/10/31)

A variety of substituted 3-arylcoumarin derivatives were synthesised through microwave radiation heating. The method has characteristics of environmental friendliness, economy, simple separation, and purification process, less by-products and high reaction yield. Those 3-arylcoumarin derivatives were screened for antioxidant, α-glucosidase inhibitory and advanced glycation end-products (AGEs) formation inhibitory. Most compounds exhibited significant antioxidant and AGEs formation inhibitory activities. Anti-diabetic activity studies showed that compounds 11 and 17 were equipotent to the standard drug glibenclamide in vivo. According to the experimental results, the target compound 35 can be used as a lead compound for the development of new anti-diabetic drugs. The whole experiment showed that anti-diabetic activity is prevalent in 3-arylcoumarins, which added a new natural skeleton to the development of anti-diabetic active drugs.

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