1333398-79-0

Basic information

• Product Name: 2'-aminomethyl-5'-(pyridin-4-ylcarbamoyl)-biphenyl-3-carboxylic acid cyclohexyl methyl ester
• Synonyms: 2'-aminomethyl-5'-(pyridin-4-ylcarbamoyl)-biphenyl-3-carboxylic acid cyclohexyl methyl ester
• CAS NO: 1333398-79-0
• Molecular Weight: 443.546
• Mol File: 1333398-79-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2'-aminomethyl-5'-(pyridin-4-ylcarbamoyl)-biphenyl-3-carboxylic acid cyclohexyl methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2'-aminomethyl-5'-(pyridin-4-ylcarbamoyl)-biphenyl-3-carboxylic acid cyclohexyl methyl ester(1333398-79-0)
• EPA Substance Registry System: 2'-aminomethyl-5'-(pyridin-4-ylcarbamoyl)-biphenyl-3-carboxylic acid cyclohexyl methyl ester(1333398-79-0)

Safety Data

• Hazardous Substances Data: 1333398-79-0(Hazardous Substances Data)

Upstream product

• 504-24-5 4-aminopyridine 
• 1333400-84-2 3-bromo-4-(tert-butoxycarbonylamino-methyl)benzoic acid 
• 1333400-86-4 3-bromo-4-(tert-butoxycarbonylamino-methyl)benzoic acid methyl ester 
• 1333400-85-3 diBoc-4-aminomethyl-3-bromo-benzoic acid methyl ester 
• 78946-25-5 3-bromo-4-(bromomethyl)benzoic acid methyl ester 
• 104901-43-1 methyl 3-bromo-4-methylbenzoate 
• 7697-26-9 3-bromo-4-methylbenzoic acid 
• 1333400-90-0 2'-(tert-butoxycarbonylamino-methyl)-5'-(pyridin-4-ylcarbamoyl)-biphenyl-3-carboxylic acid 
• 1333400-87-5 [2-bromo-4-(pyridin-4-ylcarbamoyl)-benzyl]-carbamic acid tert-butyl ester 

Relevant articles and documents

3-[2-(Aminomethyl)-5-[(pyridin-4-yl)carbamoyl]phenyl] benzoates as soft ROCK inhibitors

Clinical development of ROCK inhibitors has so far been limited by systemic or local ROCK-associated side effects. A soft drug approach, which involves predictable metabolic inactivation of an active compound to a nontoxic metabolite, could represent an a