1333400-68-2

Upstream product

• 504-24-5 4-aminopyridine 
• 1333400-65-9 3-bromo-4-(1-tert-butoxycarbonylamino-ethyl)-benzoic acid 
• 113642-07-2 2-bromo-4-carboxyacetophenone 
• 1333400-66-0 3-bromo-4-[1-(hydroximino)-ethyl]-benzoic acid 

Downstream Products

• 1333400-80-8 4-[2-(1-tert-butoxycarbonylamino-ethyl)-5-(pyridin-4-ylcarbamoyl)-phenyl]-1H-pyrrole-2-carboxylic acid 
• 1333400-83-1 4-[2-(1-tert-butoxycarbonylamino-ethyl)-5-(pyridin-4-ylcarbamoyl)-phenyl]-1H-indole-2-carboxylic acid 
• 1333400-82-0 4-[2-(1-tert-butoxycarbonylamino-ethyl)-5-(pyridin-4-ylcarbamoyl)-phenyl]-1H-pyrrole-2-carboxylic acid methyl ester 
• 1352964-98-7 C₂₉H₃₀N₄O₅ 

Relevant academic research and scientific papers

HETEROCYCLIC AMIDES AS ROCK INHIBITORS

The present invention relates to new kinase inhibitors of formula (I), more specifically ROCK inhibitors, compositions, in particular pharmaceuticals, comprising such inhibitors, and to uses of such inhibitors in the treatment and prophylaxis of disease. In particular, the present invention relates to new ROCK inhibitors, compositions, in particular pharmaceuticals, comprising such inhibitors, and to uses of such inhibitors in the treatment and prophylaxis of disease. In addition, the invention relates to methods of treatment and use of said compounds in the manufacture of a medicament for the application to a number of therapeutic indications including sexual dysfunction, inflammatory diseases, ophthalmic diseases and Respiratory diseases.