133345-52-5

Upstream product

• 90-02-8 salicylaldehyde 
• 616-29-5 1,3-Diamino-2-hydroxypropane 
• 89-95-2 2-methyl-benzyl alcohol 

Downstream Products

• 145522-01-6 N,N'-bis(2-hydroxybenzyl)-2-hydroxypropane-1,3-diamine 
• 94-93-9 N,N'-ethylenebis(2-hydroxybenzylideneimine) 

Relevant academic research and scientific papers

The synthesis, crystal structure and spectroscopic properties of a dinuclear μ-pyrazolato-N,N′-bridged dinickel(II) complex of 1,3-bis(salicylideneamino)propan-2-ol

The title compound [Ni2(L)(3,5 prz)], prz = pyrazolate with the formally pentadentate ligand L = 1,3-bis(salicylideneamino)propan-2-olate, was synthesized and identified using elemental analysis and IR spectroscopy. It crystallizes in the monoclinic space group P21/c with cell parameters a = 29.873(4), b = 11.131(2), c = 13.166(3) ?, β= 107.770(10)°, V = 4169.0(13) ?3, Z = 4, Dcal = 1.618 Mg/m 3. The nickel ions are bridged by the alkoxo group of the ligand and the N atoms of the μ-pyrazolate group. Each nickel(II) ion is coordinated by two N atoms and two O atoms, forming a square with trans-N2O 2 geometry. The Ni...Ni distance and the Ni-O-Ni angle are 3.371(1) ? and 126.4(1)°, respectively.

The effect of metal and substituent on DNA binding, cleavage activity, and cytotoxicity of new synthesized Schiff base ligands and Zn(II) complex

New water soluble Schiff base ligands [N,N?-bis{5-[(triphenylphosphonium percholorate)-methyl]salicylidine}-1,3-diamino-2-propanol] (L1) and [N,N?-bis(salicylidine)-1,3-diamino-2-propanol] (L2) and zinc (II) complex of L1: [N,N?-bis{5-[(triphenylphosphonium percholorate)-methyl]salicylidine}-1,3-diamino-2-propanol]Zn(II) were synthesized and characterized by elemental analysis, FT-IR, 1HNMR and UV–Vis spectroscopy. In vitro DNA binding of the compounds were investigated by UV–Vis absorption spectroscopy, viscosity measurement, cyclic voltammetry, fluorescence spectroscopy, and gel electrophoresis. The present study aimed to investigate the effect of metal and substituent on DNA binding, cleavage activity and cytotoxicity of new synthesized Schiff base ligands and Zn(II) complex. The order of DNA binding affinity (Kb) calculated from the absorption spectroscopy was: ZnL1 > L2 > L1. Molecular docking studies explore more details on the mode of binding and binding energies. Although the compounds revealed strong DNA binding affinity but electrophoresis studies don't show any effects on the DNA structure and single or double strand breaks. The cytotoxicity experiments against human Hepatoma (HepG2) showed the order: L1 > ZnL1 > L2.

Novel Pd(ii)-salen complexes showing high in vitro anti-proliferative effects against human hepatoma cancer by modulating specific regulatory genes

We have reported the synthesis of a novel salen ligand and its mononuclear Pd-salen complexes derived from 2-{[2-hydroxy-3-{[(E)-(2-hydroxyphenyl) methylidene]amino}propyl)imino]methyl}phenol. The newly synthesized and isolated Pd(ii) complexes have been

Oxidative cleavage of DNA by transition metal complexes: Synthesis, spectral characterization and DNA interactions of copper(II) complexes with quinquedentate Schiff base ligands

Designing of dinucleating ligands, with an additional donor atom that can bridge two metals in a more or less fixed geometry has rapidly developed in recent years. Part of the interest stems from the fact that the corresponding complexes are often studied

A perfectly linear trinuclear zinc-Schiff base complex: Synthesis, luminescence property and photocatalytic activity of zinc oxide nanoparticle

A perfectly linear trinuclear zinc(II) complex [Zn3L 2(μ-O2CCH3)2] (1) containing a (N,O)-donor Schiff base ligand, (H2L = N,N′- bis(salicyaldehydene)-1,3-diaminopropan-2-ol) has been synth

Synthesis, X-ray structural and magnetic characterizations, and epoxidation activity of a new bis(μ-acetato)(μ-alkoxo)dinuclear iron(III) complex

The synthesis, crystal structure and variable temperature magnetic measurements of a new dinuclear Fe(III) complex, [Fe2(μ 1,3-O2Cfn)(OH2)(MeOH)Cl2L] (1) [fn = furan, L = N,N′-bis(salicyaldehydene)-1,

Transesterification activity by a zinc(II)-Schiff base complex with theoretical interpretation

The article demonstrates the synthesis, structural characterization and transesterification activity of a mononuclear zinc(II) complex, [Zn(HL)(H2O)]·(H2O) (1) containing a previously reported Schiff base ligand, H3L = N,N

Synthesis, structural and DFT interpretation of a Schiff base assisted Mn(III) derivative

A mononuclear MnIII derivative, [Mn(L)(SCN)(H2O)] (1) [where H2L = N,N′-bis(salicyaldehydene)-1,3-diaminopropan-2-ol] has been synthesized and systematically characterized. In 1, the central MnIII ion is linked

Synthesis, characterization, superoxide dismutase, and antimicrobial activities of Co (II) complexes with Schiff base ligand and their hybrid proteins

Metal complexes have been reported to possess excellent free radical scavenging and antimicrobial properties. In the present study, seven linear trinuclear complexes were synthesized based on bis Schiff base ligand and complexes 1, 3–7 are reported for th

A bowl-shaped phenoxido-bridged binuclear zinc complex: Experimental and theoretical studies

A new dinuclear zinc coordination complex with di(μ-alkoxido) bridge obtained from [[H2L = N,N-(salicyaldene)-1,3-diaminopropan-2-ol] was investigated by IR, 1H- & 13C NMR spectroscopy. Single crystal X-ray analysis reveal