1333502-34-3Relevant articles and documents
Z-selective intramolecular Horner-Wadsworth-Emmons reaction for the synthesis of macrocyclic alkenes
Ando, Kaori,Sato, Kaori
, p. 1284 - 1287 (2011/03/22)
The Z-selective intramolecular Horner-Wadsworth-Emmons reaction of the substrates 7-12 (RO)2P(O)CHR′CO2Et (R′ = (CH2)nCHO) (R = Ph or o-tBuC6H4) gives the 13-18-membered cyclic alkenes selectively (up to Z:E = 97:3) in good yields using NaH in THF under high dilution conditions.