13336-73-7Relevant academic research and scientific papers
T3P-mediated one-pot synthesis of Bis(α-aminophosphonates)
Milen, Matyas,Abranyi-Balogh, Peter,Kangyal, Reka,Dancso, Andras,Frigyes, David,Keglevich, Gyoergy
, p. 245 - 255 (2014/07/22)
Two series of bis(α-aminophosphonates) were synthesized by one-pot three-component reactions using 4-phenylenediamine, an aldehyde (2 equiv) and a phosphite (2 equiv), or terephtalaldehyde, an amine (2 equiv), and a phosphite (2 equiv) together with propy
Highly efficient one-pot multi-component synthesis of α- aminophosphonates and bis-α-aminophosphonates catalyzed by heterogeneous reusable silica supported dodecatungstophosphoric acid (DTP/SiO2) at ambient temperature and their antitubercular evaluation against Mycobactrium Tuberculosis
Mulla, Shafeek A. R.,Pathan, Mohsinkhan Y.,Chavan, Santosh S.,Gample, Suwara P.,Sarkar, Dhiman
, p. 7666 - 7672 (2014/02/14)
A highly efficient one-pot multi-component reaction (MCR) protocol over DTP/SiO2 has been developed for the synthesis of α- aminophosphonate derivatives (4a-x) in excellent yields. The α-aminophosphonate derivatives were for the first time evaluated for their antitubercular activity against the M. tuberculosis H37Ra (MTB) strain. An evaluation of the data on the cytotoxicity and antimicrobial activity shows that 4n and 4v are promising antitubercular agents.
NbCl5: An efficient catalyst for one-pot synthesis of α-aminophosphonates under solvent-free conditions
Hou, Jun-Tao,Gao, Jian-Wu,Zhang, Zhan-Hui
experimental part, p. 47 - 53 (2011/09/14)
NbCl5 has been found to be a very effective catalyst for the synthesis of a variety of α-aminophosphonates through the Kabachnik-Fields reaction of carbonyl compound, amine and diethyl phosphite under solvent-free conditions. Copyright
A highly efficient bismuth salts-catalyzed route for the synthesis of α-aminophosphonates
Banik, Antara,Batta, Sahil,Bandyopadhyay, Debasish,Banik, Bimal K.
experimental part, p. 8205 - 8213 (2011/02/22)
A convenient synthesis of different types of α-amino phosphonates via one-pot solvent-free three component reactions of aldehydes, amines and phosphites catalyzed by bismuth salts has been investigated. Bismuth triflate is found to be the most effective catalyst for this reaction.
Design and one-pot synthesis of α-aminophosphonates and bis(α-aminophosphonates) by iron(III) chloride and cytotoxic activity
Rezaei, Zahra,Firouzabadi, Habib,Iranpoor, Nasser,Ghaderi, Abbas,Jafari, Mohammad Reza,Jafari, Abbas Ali,Zare, Hamid Reza
experimental part, p. 4266 - 4275 (2009/12/24)
In this study, we used a solution of FeCl3 in THF to facilitate the Mannich-type reaction of aldehyde, amine and phosphite compounds to form corresponding α-aminophosphonates in a one-pot, three-component reaction. Selected α-aminophosphonates
An eco-friendly procedure for the efficient synthesis of dialkyl α-aminophosphonates in aqueous media
Sobhani, Sara,Safaei, Elham,Asadi, Mozaffar,Jalili, Fariba
, p. 3313 - 3317 (2008/12/22)
A new, convenient and high yielding procedure for the preparation of diethyl α-aminophosphonates in water by one-pot reaction of aldehydes, amines, tri/dialkyl phosphites in the presence of a low catalytic amount of [Cu(3,4-tmtppa)](MeSO4)4 (0.16 mol%) as a highly stable and re-usable catalyst is described.
SYNTHESIS, NMR INVESTIGATION AND FAB-MS CHARACTERIZATION OF 1-AMINO-2-ARYLMETHYL-DIPHOSPHONATE ESTERS
Failla, Salvatore,Finocchiaro, Paolo,Hagele, Gerhard,Rapisardi, Roberto
, p. 79 - 90 (2007/10/02)
Variously substituted amino aryl-methyl-diphosphonate ethyl esters have been prepared in good yields by adding diethyl phosphonate to the corresponding Schiff bases.All compounds were characterized by NMR and MS-FAB techniques, which reveal the presence o
