133368-03-3

Usage

General Description

1,1'-Biphenyl, 4-(1-fluoroethenyl)- is a chemical compound that is also known as 4-(1-fluoroethenyl)biphenyl or 4-(1-fluoroethenyl)biphenyl. It is a synthetic organic compound that belongs to the class of biphenyls. This chemical compound is commonly used as a building block in the synthesis of other organic compounds and is also utilized in research and development activities. It has potential applications in the pharmaceutical, agrochemical, and material science industries. Additionally, it is important to handle this chemical compound with care, as it may possess certain hazards or risks associated with its handling and use in various industrial processes.

Upstream product

• 92-66-0 4-bromo-1,1'-biphenyl 
• 75867-42-4 ([1,1'-biphenyl]-4-ylethynyl)trimethylsilane 
• 29079-00-3 4-ethynyl-1,1'-biphenyl 

Relevant academic research and scientific papers

Gold N-Heterocyclic Carbene Catalysts for the Hydrofluorination of Alkynes Using Hydrofluoric Acid: Reaction Scope, Mechanistic Studies and the Tracking of Elusive Intermediates

An efficient and chemoselective methodology deploying gold-N-heterocyclic carbene (NHC) complexes as catalysts in the hydrofluorination of terminal alkynes using aqueous HF has been developed. Mechanistic studies shed light on an in situ generated catalyst, formed by the reaction of Br?nsted basic gold pre-catalysts with HF in water, which exhibits the highest reactivity and chemoselectivity. The catalytic system has a wide alkyl substituted-substrate scope, and stoichiometric as well as catalytic reactions with tailor-designed gold pre-catalysts enable the identification of various gold species involved along the catalytic cycle. Computational studies aid in understanding the chemoselectivity observed through examination of key mechanistic steps for phosphine- and NHC-coordinated gold species bearing the triflate counterion and the elusive key complex bearing a bifluoride counterion.