133386-77-3Relevant academic research and scientific papers
Thietane-fused β-Lactams via Photochemical Cycloaddition Reaction of N-(α,β-Unsaturated Carbonyl)thioamides
Sakamoto, Masami,Yanase, Tohru,Fujita, Tsutomu,Watanabe, Shoji,Aoyama, Hiromu,Omote, Yoshimori
, p. 403 - 407 (2007/10/02)
Photolysis of N-(α,β-unsaturated carbonyl)thioamides gave thietane-fused β-lactams in good yields, whereas some of the thioimides formed thiones via β-hydrogen abstraction of the thiocarbonyl group.Substituents at the α-position to the carbonyl carbon lead to a preference for cyclization over β-hydrogen abstraction.From a sensitisation experiment this reaction was shown to proceed via an n?* triplet excited state.
