5310-14-5

Basic information

• Product Name: N-methylthiobenzamide
• Synonyms: N-methylthiobenzamide;N-methylbenzenecarbothioamide
• CAS NO: 5310-14-5
• Molecular Formula: C₈H₉NS
• Molecular Weight: 151.23
• Mol File: 5310-14-5.mol
• Article Data: 38

Chemical Properties

• Melting Point: 81.5 °C(Solv: water (7732-18-5))
• Boiling Point: 225.1°C at 760 mmHg
• Flash Point: 90°C
• Appearance: /
• Density: 1.098g/cm³
• Vapor Pressure: 0.0879mmHg at 25°C
• Refractive Index: 1.6
• PKA: 12.45±0.70(Predicted)
• CAS DataBase Reference: N-methylthiobenzamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-methylthiobenzamide(5310-14-5)
• EPA Substance Registry System: N-methylthiobenzamide(5310-14-5)

Safety Data

• Hazardous Substances Data: 5310-14-5(Hazardous Substances Data)

Usage

InChI:InChI=1/C8H9NS/c1-9-8(10)7-5-3-2-4-6-7/h2-6H,1H3,(H,9,10)

Upstream product

• 88070-48-8 N-methylbenzamide 
• 556-61-6 methyl thioisocyanate 
• 98-09-9 benzenesulfonyl chloride 
• 623-11-0 1-methyl-4-nitrosobenzene 
• 74-89-5 methylamine 
• 942-91-6 Carboxymethyl dithiobenzoate 
• 1280-28-0 Anhydro-5-hydroxy-3-methyl-2-phenylthiazolium hydroxide 
• 622-29-7 N-Benzylidenemethylamine 
• 108-86-1 bromobenzene 
• 103-67-3 benzyl-methyl-amine 
• 123-39-7 N-Methylformamide 
• 536-74-3 phenylacetylene 
• 100-44-7 benzyl chloride 
• 100-51-6 benzyl alcohol 

Downstream Products

• 58065-86-4 N-methyl-N-trimethylsilanyl-thiobenzamide 
• 3472-76-2 (dichloro-phenyl-methyl)-carbonimidic acid dichloride 
• 91929-53-2 N-Methyl-thiobenzamid-S-oxyd (N-Methyl-thiobenzoyl-S-oxyd) 
• 26309-44-4 3-methyl-4-phenyl-[1,2,3]dithiazetium; chloride 
• 4115-21-3 N-methyl-N'-tosylbenzimidamide 
• 59073-57-3 N-Methylthiobenzimidsaeure-methylester-hydroiodid 
• 112423-02-6 3-Methyl-6-oxo-2,5-diphenyl-6H-1,3-thiazin-3-ium-4-olat 
• 89861-53-0 C₁₂H₁₇NS₂ 
• 83241-86-5 N-Methyl-N-((E)-3-oxo-3-phenyl-propenyl)-thiobenzamide 
• 83241-79-6 N-Methyl-thiobenzimidic acid (Z)-3-oxo-3-phenyl-propenyl ester 
• 83251-67-6 N-Methyl-thiobenzimidic acid (Z)-3-oxo-3-phenyl-propenyl ester; compound with perchloric acid 
• 17453-03-1 2,5-Bis-<4-methoxy-phenyl>-1,3,4-thiadiazol 
• 1456-67-3 2-(4'-methoxyphenyl)-5-phenyl-1,3,4-thiadiazole 
• 88070-48-8 N-methylbenzamide 

Relevant articles and documents

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Method for preparing aryl thioamide compound

The invention discloses a method for preparing an aryl thioamide compound. The method comprises the following steps: under the protection of inert gas, performing stirring to react for 6-12 hours at the reaction temperature of room temperature to 60 DEG C by taking aryl methanol as a substrate, sublimed sulfur as a sulfur source, an alkali metal complex formed by combining alkali metal salt and ligand as a catalyst, alkali as an accelerant, formamide as a solvent and an amine source; and carrying out post-treatment on the reaction product to obtain the aryl thioamide compound. According to theinvention, cheap and easily available aryl methanol is used as a substrate for three-component reaction to prepare the corresponding thioamide compound; the method for preparing the aryl thioamide compound has the technical advantages of simple technological process, high yield, less pollution, safety, environmental protection, greenness, mildness and the like.

Transition-Metal-Free Cleavage of C-C Triple Bonds in Aromatic Alkynes with S8 and Amides Leading to Aryl Thioamides

A novel transition-metal-free cleavage reaction of C-C triple bonds in aromatic alkynes with S8 and amides furnishes aryl thioamides in moderate to excellent yields. The remarkable features of this thioamidation include the metal-free cleavage of C-C triple bond, mild reaction conditions, as well as wide substrate scope that is particularly compatible with some internal aromatic alkynes and acetamides.