1333899-73-2Relevant articles and documents
Design, synthesis, and bioactivities of novel oxadiazole-substituted pyrazole oximes
Dai, Hong,Chen, Jia,Li, Gang,Ge, Shushan,Shi, Yujun,Fang, Yuan,Ling, Yong
, p. 950 - 953 (2017/02/10)
A series of novel pyrazole oxime derivatives containing a substituted oxadiazole group were designed and synthesized. The bioassay results indicated that some title compounds displayed good acaricidal and insecticidal activities against Tetranychus cinnabarinus, Aphis medicaginis, Oriental armyworm, and Nilaparvata lugens. Especially, compounds 7a, 7b, and 7c had 80%, 90%, and 90% insecticidal activities against A. medicaginis at 20 μg/mL, respectively. Interestingly, some of the designed compounds displayed wonderful fungicidal activities in vivo against cucumber Pseudoperonospora cubensis. Furthermore, compounds 7a (EC50= 4.97 μg/mL) and 7h (EC50= 0.51 μg/mL) showed excellent fungicidal activity against P. cubensis comparable or better than that of the control Pyraclostrobin (EC50= 4.59 μg/mL).
Design, synthesis, and antibacterial evaluation of new Schiff's base derivatives bearing nitroimidazole and pyrazole nuclei as potent E. coli FabH inhibitors
Sangani, Chetan B.,Makwana, Jigar A.,Duan, Yong-Tao,Tarpada, Umesh P.,Patel, Yogesh S.,Patel, Ketan B.,Dave, Vivek N.,Zhu, Hai-Liang
, p. 10137 - 10149 (2016/01/12)
New Schiff's base derivatives 5a-j have been synthesized by reaction between 5-aryloxypyrazole-4-carbaldehydes 3a-j and 2-(2-methyl-5-nitro-1Himidazol- 1-yl)acetohydrazide 4 in the presence of nickel (II) nitrate as a catalyst in ethanol at room temperatu
Microwave-assisted synthesis of novel 4H-chromene derivatives bearing phenoxypyrazole and their antimicrobial activity assessment
Sangani, Chetan B.,Shah, Nimesh M.,Patel, Manish P.,Patel, Ranjan G.
, p. 1165 - 1174 (2012/11/13)
A new series of 4H-chromene derivatives 4a-p bearing the 5-phenoxypyrazole nucleus were synthesized under microwave irradiation by the reaction of 5-phenoxypyrazole-4-carbaldehydes 1a-h, malononitrile 2 and compounds 1,3-cyclohexanedione and dimedone (3a