13339-02-1 Usage
Description
2-PIPERAZIN-1-YL-PHENYLAMINE, a phenylamine derivative with the molecular formula C12H17N3, is a chemical compound that features a piperazine ring. It is widely recognized in the pharmaceutical industry for its role in the synthesis of a variety of drugs and medications. 2-PIPERAZIN-1-YL-PHENYLAMINE's unique chemical structure and pharmacological properties have positioned it as a promising candidate for therapeutic applications, particularly in the realms of antipsychotic, anti-anxiety, and mood disorder treatments.
Uses
Used in Pharmaceutical Industry:
2-PIPERAZIN-1-YL-PHENYLAMINE is used as a key intermediate in the synthesis of various drugs and medications, leveraging its chemical properties to contribute to the development of new therapeutic agents.
Used in Antipsychotic Medications:
2-PIPERAZIN-1-YL-PHENYLAMINE is utilized as an active pharmaceutical ingredient in the formulation of antipsychotic drugs, targeting the treatment of psychotic disorders by modulating neurotransmitter activity in the brain.
Used in Anti-Anxiety Agents:
2-PIPERAZIN-1-YL-PHENYLAMINE serves as a constituent in anti-anxiety medications, aiming to alleviate symptoms of anxiety by influencing specific receptors and pathways involved in the stress response.
Used in Treatment of Depression and Mood Disorders:
2-PIPERAZIN-1-YL-PHENYLAMINE is explored for its potential in the development of treatments for depression and other mood disorders, given its capacity to impact neurochemical processes associated with mood regulation.
Used in Medicinal Chemistry Research and Development:
2-PIPERAZIN-1-YL-PHENYLAMINE is employed as a subject of research in medicinal chemistry, with the goal of uncovering new applications and optimizing its therapeutic potential for various medical conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 13339-02-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,3,3,3 and 9 respectively; the second part has 2 digits, 0 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 13339-02:
(7*1)+(6*3)+(5*3)+(4*3)+(3*9)+(2*0)+(1*2)=81
81 % 10 = 1
So 13339-02-1 is a valid CAS Registry Number.
InChI:InChI=1/C10H15N3/c11-9-3-1-2-4-10(9)13-7-5-12-6-8-13/h1-4,12H,5-8,11H2
13339-02-1Relevant articles and documents
REGULATOR OF NITROGEN-CONTAINING HETEROAROMATIC DERIVATIVES, PREPARATION METHOD THEREFOR AND USE THEREOF
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, (2021/08/27)
The present invention relates to a regulator of nitrogen-containing heteroaromatic derivatives, a preparation method therefor and the use thereof. In particular, the present invention relates to a compound as shown in the general formula (I), a preparation method therefor and a pharmaceutical composition containing the compound, and the use thereof as a protein tyrosine phosphatase-2C (SHP2) inhibitor in the treatment of diseases or conditions such as leukemia, neuroblastoma, melanoma, breast cancer, lung cancer and colorectal cancer, wherein the definition of each substituent in the general formula (I) is the same as that in the description.
Potent 2′-aminoanilide inhibitors of cFMS as potential anti-inflammatory agents
Patch, Raymond J.,Brandt, Benjamin M.,Asgari, Davoud,Baindur, Nand,Chadha, Naresh K.,Georgiadis, Taxiarchis,Cheung, Wing S.,Petrounia, Ioanna P.,Donatelli, Robert R.,Chaikin, Margery A.,Player, Mark R.
, p. 6070 - 6074 (2008/03/18)
A series of 2′-aminoanilides have been identified which exhibit potent and selective inhibitory activity against the cFMS tyrosine kinase. Initial SAR studies within this series are described which examine aroyl and amino group substitutions, as well as the introduction of hydrophilic substituents on the benzene core. Compound 47 inhibits the isolated enzyme (IC50 = 0.027 μM) and blocks CSF-1-induced proliferation of bone marrow-derived macrophages (IC50 = 0.11 μM) and as such, serves as a lead candidate for further optimization studies.