1334160-30-3

Upstream product

• 1260111-81-6 N-(acetyl) dichlorofluoromethyl phenyl sulfilimine 
• 1334160-28-9 N-(acetyl) dichlorofluoromethyl phenyl sulfoximine 
• 1111-78-0 ammonium carbamate 
• 130755-47-4 (dichlorofluoromethyl)(phenyl)sulfide 

Downstream Products

• 1334160-38-1 CF₃O₃S^(1-)*C₉H₁₁Cl₂FNOS⁽¹⁺⁾ 
• 1334160-40-5 N,N-(dimethylamino)-S-phenyl-S-dichlorofluoromethyloxosulfonium tetrafluoroborate 
• 1334160-32-5 dichlorofluoromethyl phenyl N-trifluoromethanesulfonyl sulfoximine 
• 1334160-34-7 N-methyl-S-phenyl-S-dichlorofluoromethylsulfoximine 
• 1448157-78-5 O-(2,2,2-trichloroethyl) N-{[dichloro(fluoro)methyl]oxophenyl-λ6-sulfanylidene}carbamoate 
• 1448157-64-9 N-{[dichloro(fluoro)methyl]-oxo-(phenyl)-λ6-sulfanylidene}benzamide 

Relevant academic research and scientific papers

One-Pot Synthesis of Aryl- and Alkyl S-Perfluoroalkylated NH-Sulfoximines from Sulfides

A general efficient one-pot synthesis of S-perfluoroalkylated NH-sulfoximines from sulfides has been developed using phenyliodine diacetate (PIDA) and ammonium carbamate. Remarkable rate enhancement with trifluoroethanol was observed, presumably due to H-bonding effects. These mild and metal-free conditions are compatible with -CH2F, -CFCl2, -CF2H, -CF2Br, -C4F9, and -CF3 groups, in both the alkyl- and aryl series. Based on a 19F NMR analysis, a λ6-acetoxysulfanenitrile intermediate was proposed.

Sulfoximines as a versatile scaffold for electrophilic fluoroalkylating reagents

New electrophilic fluoroalkylating agents based on the sulfoximine skeleton as a common platform are described. We demonstrate the importance of the activating group, attached to the nitrogen, and its specificity for the fluorinated group to be delivered.