1334212-46-2Relevant academic research and scientific papers
An unexpected synthesis of 3,5-diaryl-1,2,4-thiadiazoles from thiobenzamides and methyl bromocyanoacetate
Mayhoub, Abdelrahman S.,Kiselev, Evgeny,Cushman, Mark
supporting information; experimental part, p. 4941 - 4943 (2011/10/07)
Aryl thioamides undergo very rapid condensation in the presence of methyl bromocyanoacetate to provide quantitative yields of 3,5-diaryl-1,2,4- thiadiazoles with an easy work-up and a high degree of product purity. The method can be scaled up with no loss in efficiency.
