1334218-22-2Relevant academic research and scientific papers
Synthesis of 1,6-dihydropyrrolo[2,3-g]indazoles using Larock indole annulation
Gavara, Laurent,Anizon, Fabrice,Moreau, Pascale
, p. 7330 - 7335 (2011/10/09)
The synthesis of 1,6-dihydropyrrolo[2,3-g]indazole derivatives is described. The indolic ring system is constructed via a Larock palladium-catalyzed annulation using terminal and internal alkynes. Additionally, when using internal alkynes for this reaction, we found that a directing effect on regioselectivity was mediated by the ester group of alkyl 3-substituted propiolate derivatives.
