59601-91-1

Basic information

• Product Name: 5,6-dinitro-1H-indazole
• Synonyms: 5,6-dinitro-1H-indazole;Einecs 261-823-0;NSC 49913
• CAS NO: 59601-91-1
• Molecular Formula: C₇H₄N₄O₄
• Molecular Weight: 208.13106
• EINECS: 261-823-0
• Product Categories: Aldehyde Labeling Reagents;Aromatics
• Mol File: 59601-91-1.mol
• Article Data: 3

Chemical Properties

• Melting Point: 234-235°C
• Boiling Point: 506.4°C at 760 mmHg
• Flash Point: 260°C
• Appearance: /
• Density: 1.752g/cm³
• Vapor Pressure: 7.07E-10mmHg at 25°C
• Refractive Index: 1.777
• Storage Temp.: Refrigerator
• CAS DataBase Reference: 5,6-dinitro-1H-indazole(CAS DataBase Reference)
• NIST Chemistry Reference: 5,6-dinitro-1H-indazole(59601-91-1)
• EPA Substance Registry System: 5,6-dinitro-1H-indazole(59601-91-1)

Safety Data

• Hazardous Substances Data: 59601-91-1(Hazardous Substances Data)

Usage

Chemical Properties

Light Yellow Solid

Uses

5,6-Dinitroindazole (cas# 59601-91-1) is a compound useful in organic synthesis.

InChI:InChI=1/C7H4N4O4/c12-10(13)6-1-4-3-8-9-5(4)2-7(6)11(14)15/h1-3H,(H,8,9)

Upstream product

• 7597-18-4 6-nitroindazole 

Downstream Products

• 1334218-39-1 5-nitro-8-phenyl-1,6-dihydropyrrolo[2,3-g]indazole 
• 1334218-32-4 8-ethyl-5-nitro-7-phenyl-1-(tetrahydro-2H-pyran-2-yl)-1,6-dihydropyrrolo[2,3-g]indazole 
• 1334218-30-2 7-ethyl-5-nitro-8-phenyl-1-(tetrahydro-2H-pyran-2-yl)-1,6-dihydropyrrolo[2,3-g]indazole 
• 1334218-22-2 C₂₂H₂₂N₄O₄ 
• 1334218-24-4 C₂₂H₂₂N₄O₄ 
• 1334218-08-4 5-nitro-8-phenyl-1-(tetrahydro-2H-pyran-2-yl)-1,6-dihydropyrrolo[2,3-g]indazole 
• 1276662-12-4 2-benzyl-5,6-dinitro-2H-indazole 
• 1276662-11-3 1-benzyl-5,6-dinitro-1H-indazole 
• 98549-93-0 5,6-dihydroxy-1H-indazole 
• 7404-68-4 1H-indazole-5,6-diamine 

Relevant articles and documents

BENZIMIDAZOLE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS AND USES THEREOF

The present invention relates to benzimidazole derivatives and their pharmaceutical compositions and uses, specifically to benzimidazole derivatives of Formula (I), or their stereoisomer, pharmaceutically acceptable salt or solvates thereof, in which R1, R2, R3, R4, R5 and n have the definitions in the description; the present invention further relates to a pharmaceutical composition containing the compounds, methods for preparing the compounds, and use of the compounds for manufacturing of a medicament for prophylaxis and/or treatment of peptic ulcer, ulcer hemorrhage and diseases associated with gastric acid.

Synthesis and biological activities of pyrazolo[3,4-g]quinoxaline derivatives

The synthesis of new pyrazolo[3,4-g]quinoxaline derivatives, as well as their Pim kinases (Pim-1, Pim-2, Pim-3) inhibitory potencies and in vitro antiproliferative activities toward a human fibroblast primary culture and three human solid cancer cell lines (PA1, PC3 and DU145) are described. The results obtained in this preliminary structure-activity relationship study have pointed out that most of the compounds in this series exhibited interesting in vitro Pim-3 kinase inhibitory potencies. Moreover, some of the tested compounds have demonstrated favorable antiproliferative potencies.