133442-63-4

Upstream product

• 139014-84-9 1-[(S)-(R)-3-Chloro-2-((E)-3-chloro-allyloxy)-3,3-difluoro-propane-1-sulfinyl]-4-methyl-benzene 
• 133359-89-4 1-((S)-(R)-2-Allyloxy-3-chloro-3,3-difluoro-propane-1-sulfinyl)-4-methyl-benzene 
• 133343-60-9 1-[(S)-(R)-3-Chloro-2-(2-chloro-allyloxy)-3,3-difluoro-propane-1-sulfinyl]-4-methyl-benzene 
• 133343-54-1 1-((S)-(S)-2-Allyloxy-3-chloro-3,3-difluoro-propane-1-sulfinyl)-4-methyl-benzene 

Downstream Products

• 136848-14-1 trans-3,3-difluoro-4-methyl-2-<(p-tolylsulphonyl)methyl>-tetrahydrofuran 

Relevant academic research and scientific papers

Intramolecular trapping of difluoroalkyl radicals by tethered olefin in the asymmetric synthesis of 2,4-disubstituted-3,3-difluorotetrahydrofurans

Optically pure propenyl ethers of 3-sulphenyl-, 3-sulphuryl-, and 3-sulphonyl-1-chloro-1,1-difluoropropan-2-ols were submitted to radical cyclization affording, with moderate to high diastereoselectivity. 3,3-difluorotetrahydrofurans containing in 2 and 4

ASYMMETRIC SYNTHESIS OF 2,4-DISUBSTITUTED 3,3-DIFLUOROTETRAHYDROFURANS BY RADICAL CYCLIZATION OF FLUORINATED SULPHINYL CHIRONS

The title compounds have been obtained with medium to high diastereoselection by radical cyclization of the optically pure fluorinated sulphinyl chirons 7a-e.