1334473-06-1

Basic information

• Product Name: 2-(2-(4-chlorophenyl)-2-oxoethyl)-7-methoxy-2-methylbenzofuran-3(2H)-one
• Synonyms: 2-(2-(4-chlorophenyl)-2-oxoethyl)-7-methoxy-2-methylbenzofuran-3(2H)-one
• CAS NO: 1334473-06-1
• Molecular Weight: 330.768
• Mol File: 1334473-06-1.mol

Chemical Properties

• CAS DataBase Reference: 2-(2-(4-chlorophenyl)-2-oxoethyl)-7-methoxy-2-methylbenzofuran-3(2H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2-(4-chlorophenyl)-2-oxoethyl)-7-methoxy-2-methylbenzofuran-3(2H)-one(1334473-06-1)
• EPA Substance Registry System: 2-(2-(4-chlorophenyl)-2-oxoethyl)-7-methoxy-2-methylbenzofuran-3(2H)-one(1334473-06-1)

Safety Data

• Hazardous Substances Data: 1334473-06-1(Hazardous Substances Data)

Upstream product

• 104-88-1 4-chlorobenzaldehyde 
• 58758-45-5 3-methoxy-2-(prop-2-yn-1-yloxy)benzaldehyde 

Relevant articles and documents

Efficient synthesis of benzofuranones: N-heterocyclic carbene (NHC)/base-catalyzed hydroacylation-stetter-rearrangement cascade

A N-heterocyclic carbene/base-catalyzed cascade reaction leading to the formation of functionalized benzofuranones is reported. The reaction proceeds via an intramolecular hydroacylation of unactivated alkynes followed by an intermolecular Stetter reactio

A versatile combined N-heterocyclic carbene and base-catalyzed multiple cascade approach for the synthesis of functionalized benzofuran-3-(2H)-ones

Functionalized 2,2-disubstituted benzofuran-3-(2H)-ones have been synthesized from simple aldehyde building blocks in a combined NHC- and base-catalyzed one-pot cascade reaction in moderate to excellent yields. This modular approach comprises a NHC-catalyzed hydroacylation/Stetter reaction sequence followed by a retro-Michael, 1,3-H shift and oxa-Michael cascade rearrangement promoted by strong bases.