1334531-20-2

Upstream product

• 3282-30-2 pivaloyl chloride 
• 445-03-4 4-chloro-2-(trifluoromethyl)aniline 
• 1334531-19-9 methyl 4-[(4-chloro-2-[(S)-hydroxy(2-methoxyphenyl)methyl]-6-methylphenyl)(2,2-dimethylpropyl)amino]-4-oxobutanoate 
• 1334531-18-8 (5-chloro-2-[(2,2-dimethylpropyl)amino]-3-methylphenyl)(2-methoxyphenyl)methanol 
• 1334531-17-7 N-(4-chloro-2-[hydroxy(2-methoxyphenyl)methyl]-6-(trifluoromethyl)phenyl)-2,2-dimethylpropanamide 
• 1007652-06-3 N-[4-chloro-2-(trifluoromethyl)phenyl]-2,2-dimethylpropanamide 

Downstream Products

• 1334531-21-3 ethyl (3S)-1-(4-[(4-chloro-2-[(S)-hydroxy(2-methoxyphenyl)methyl]-6-methylphenyl)(2,2-dimethylpropyl)amino]-4-oxobutanoyl)piperidine-3-carboxylate 

Relevant academic research and scientific papers

Discovery of atrop fixed alkoxy-aminobenzhydrol derivatives: Novel, highly potent and orally efficacious squalene synthase inhibitors

We have recently reported the discovery of the new benzhydrol template, which has a highly potent inhibitory activity for squalene synthase, as typified by compound 1 (SSI IC50 = 0.85 nM). However, it was composed of a pair of easy rotatable at