1334547-75-9Relevant academic research and scientific papers
Synthesis, Reactivity, and Bonding of Gold(I) Fluorido-Phosphine Complexes
Rachor, Simon G.,Müller, Robert,Wittwer, Philipp,Kaupp, Martin,Braun, Thomas
, p. 357 - 367 (2022/01/03)
Gold(I) fluorido complexes with phosphine ligands have been synthesized from their respective iodido precursors. The bonding situation in comparison between complexes bearing phosphines and N-heterocyclic carbenes (NHCs) was explored quantum-chemically, obtaining similar results for both. Calculations of the 19F NMR chemical shifts match the experimental values well, including the approximately 40 ppm low-field shifts for the phosphine complexes compared to the NHC complexes, in spite of similar negative charges on fluorine. The reactivity of the highly water-sensitive gold(I) fluorido complexes was studied, resulting in substitution at the metal using trimethylsilyl reagents. The compounds studied were characterized using NMR as well as X-ray diffraction methods.
Gold-Catalyzed Oxidative Cyclization/Aldol Addition of Homopropargyl Alcohols with Isatins
Cai, Ju,Wang, Xin,Qian, Yu,Qiu, Lihua,Hu, Wenhao,Xu, Xinfang
supporting information, p. 369 - 372 (2019/01/11)
A novel gold-catalyzed oxidative cyclization/aldol addition of homopropargyl alcohols with isatins has been developed that provides an effective access to the 3-hydroxyoxindoles in high yields under mild reaction conditions with high diastereoselectivities. In comparison with disclosed transformations of alkyne oxidations via an α-oxo gold carbene route, this is the first example of an aldol-type interception of an ylide (or its enolate form) intermediate with alkyne as a safe and readily available nondiazo carbene precursor.
