133475-74-8

Upstream product

• 131802-36-3 ((4S,5S)-2,2-dimethyl-5-pentyl-1,3-dioxolan-4-yl)methyl 4-methylbenzenesulfonate 
• 105499-53-4 [(4R,5S)-2,2-Dimethyl-5-((Z)-pent-2-enyl)-[1,3]dioxolan-4-yl]-methanol 
• 119238-60-7 (4S,5S)-2,2-dimethyl-4-(hydroxymethyl)-5-pentyl-1,3-dioxolane 
• 86795-44-0 3,4-O-isopropylidene-2-deoxy-D-ribose 
• 88557-31-7 ((4R,5S)-2,2-dimethyl-5-pentyl-1,3-dioxolan-4-yl)methanol 
• 88557-32-8 (2S,3S)-2,3-isopropylidenedioxyoctanal 
• 105499-54-5 (4R,5S)-2,2-Dimethyl-5-pentyl-[1,3]dioxolane-4-carbaldehyde 
• 2351-90-8 Ethyl oct-2-enoate 
• 106031-54-3 (2S,3S)-Octane-1,2,3-triol 
• 98-59-9 p-toluenesulfonyl chloride 
• 136031-99-7 (2R,3S)-ethyl 2,3-dihydroxyoctanoate 

Relevant academic research and scientific papers

Enantioselective synthesis of C1-C4 and C5-C14 fragments of cytospolide D

A convergent approach for the synthesis of the two key fragments (C1-C4 and C5-C14) of cytospolide D is described. Key transformations include MacMillan’s crossed aldol, Sharpless asymmetric dihydroxylation (AD) and Mitsunobu inversion reactions. (Figure

Synthesis of chiral epoxy alcohols: Synthesis of (+)-disparlure

(2R,3S)-1,2-Epoxy alcohols 1, (2S,3S)-2,3-epoxy alcohols 2, and (2S,3S)-1,2-epoxy alcohols 3 were prepared from readily available (-)-2-deoxy-D-ribose. Using epoxy alcohol 3b as a chiral synthon, (+)-disparlure, the pheromone of the gypsy moth, Porthetria