1334790-94-1

Basic information

• Product Name: C₁₃H₇Cl₃N₄O₆
• Synonyms: C₁₃H₇Cl₃N₄O₆
• CAS NO: 1334790-94-1
• Molecular Weight: 421.581
• Mol File: 1334790-94-1.mol

Chemical Properties

• CAS DataBase Reference: C₁₃H₇Cl₃N₄O₆(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₃H₇Cl₃N₄O₆(1334790-94-1)
• EPA Substance Registry System: C₁₃H₇Cl₃N₄O₆(1334790-94-1)

Safety Data

• Hazardous Substances Data: 1334790-94-1(Hazardous Substances Data)

Upstream product

• 3107-19-5 3,5-dichloro-4-fluoro-nitrobenzene 
• 1416982-60-9 2-amino-6-chloro-3,5-dinitrotoluene 
• 99-30-9 4-nitro-2,6-dichloroaniline 
• 51676-76-7 2,6-dichloro-3,5-dinitrotoluene 

Downstream Products

• 1334791-03-5 C₁₄H₁₁Cl₂N₅O₆ 
• 1334792-00-5 C₁₅H₉Cl₂F₃N₄O₇ 

Relevant articles and documents

Method of preparing SYP-14288

The invention belongs to the field of organic synthesis and particularly relates to a preparation method of SYP-14288. The method includes the steps of: adding a reaction solvent A to 2,6-dichloro-3,5-dinitrotoluene, adding dropwisely ammonia water or feeding ammonia gas to the solution at from 0 DEG C to reflux temperature of the solvent A, continuously performing the reaction for 1-10 h, and removing the solvent after the reaction is finished to obtain an intermediate substituted ammoniated substance; performing a reaction to the substituted ammoniated substance, 3,5-dichloro-4-fluoronitrobenzene, an alkali and a reaction solvent B for 1-20 h at from room temperature to reflux condition of the solvent B; and removing the solvent after the reaction is finished, performing post-treatment to obtain a crude product, and re-crystallizing the crude product to obtain the product, SYP-14288. The product SYP-14288 is high in purity and yield. The method employs easy-to-obtained raw materials, has simple operations and mild reaction conditions, and is suitable for industrial production.

USE OF SUBSTITUTED DIPHENYLAMINE COMPOUNDS IN PREPARING ANTI-TUMOUR DRUGS

The invention relates to substituted diphenylamine compounds using as antitumor agents. The structure of the compounds is represented as the general formula (I): The groups are as defined as specification. The compound represented by formula (I) showed po

SUBSTITUTE DIPHENYLAMINE COMPOUNDS USE THEREOF AS ANTITUMOR AGENTS

The invention relates to substituted diphenylamine compounds using as antitumor agents. The structure of the compounds is represented as the general formula (I): The groups are as defined as specification. The compound represented by formula (I) showed potent antitumor activity, especially to cure or alleviate the cancer causing by cancer cells of human tissue or organ. The preferred cancers are: colon cancer, liver cancer, lymph cancer, lung cancer, esophageal cancer, breast cancer, central nervous system cancer, melanoma, ovarian cancer, cervical cancer, renal cancer, leukemia, prostatic cancer, pancreatic cancer, bladder cancer, rectal cancer, osteosarcoma, nasopharynx cancer or stomach cancer.

SUBSTITUTED DIPHENYLAMINE COMPOUNDS, PREPARATION METHOD AND USE THEREOF

Substituted diphenylamine compounds of general formula I are provided, in which each substituted group is defined as in the description. The compounds of general formula I have broad-spectrum fungicidal activity in the field of agriculture. Furthermore, the preparation methods of the above compounds are simple.

Substituted Diphenylamine Compounds, Preparation Method and Use Thereof

Substituted diphenylamine compounds of general formula I are provided, in which each substituted group is defined as in the description. The compounds of general formula I have broad-spectrum fungicidal activity in the field of agriculture. Furthermore, the preparation methods of the above compounds are simple.