13348-41-9

Upstream product

• 111-69-3 hexanedinitrile 
• 108-94-1 cyclohexanone 
• 25344-25-6 N,N'-Dicyclohexyl-adipinsaeure-diamid 
• 694-83-7 rac-diaminocyclohexane 
• 124-09-4 1,6-Hexanediamine 
• 108-10-1 4-methyl-2-pentanone 
• 111-50-2 Adipic acid dichloride 
• 108-91-8 cyclohexylamine 

Downstream Products

• 850481-12-8 3-[[6-[(2-cyanoethyl)cyclohexylamino]hexyl]cyclohexylamino]propionitrile 
• 850481-16-2 N,N'-bis(3-aminopropyl)-N,N'-dicyclohexylhexane-1,6-diamine 

Relevant academic research and scientific papers

The reductive amination of cyclohexanone with 1,6-diaminohexane over alumina B modified Cu-Cr-La/γ-Al2O3

The reductive amination of cyclohexanone with 1,6-diaminohexane over alumina B modified Cu-Cr-La/γ-Al2O3 was investigated. The experimental results indicated that the doped alumina B remarkably increased the selectivity of N, N′-dicy

CHAIN EXTENDERS

This invention provides chain extender compositions. These compositions comprise aliphatic secondary diamines in which the amino hydrocarbyl groups are different from each other. Processes for producing polyurethanes, polyureas, and polyurea-urethanes using these aliphatic secondary diamines are also provided.

PREPARATION OF SECONDARY DIAMINES

This invention provides a process for forming secondary diamines. The process comprises bringing together i) at least one aliphatic cyclic ketone, ii) at least one aliphatic primary diamine, iii) hydrogen, and iv) a hydrogenation catalyst. The aliphatic primary diamine is isophoronediamine or an aliphatic primary α,ω-diamine, and the hydrogenation catalyst is selected from platinum on carbon, palladium on carbon, sulfided platinum on carbon, sulfided palladium on carbon, and a mixture of any two of the foregoing. The process is conducted at a temperature in the range of about 200C to about 750C and at a hydrogen pressure in the range of about 1 to about 95 pounds per square inch gauge, such that a secondary diamine is formed.

Allosteric modulators of the tertiary alkanebisamino-type. Variation of the substitution of the middle chain nitrogens

Synthesis pathways of high flexibility for variously substituted alkanebisamine-type allosteric modulators of muscarinic receptors capable of passing the blood-brain barrier were developed starting either from N,N′-(hexane-1,6-diyl)bistosylamide or adipic