133486-62-1 Usage
Description
1-(BROMOMETHYL)-3-METHOXY-2-NITROBENZENE, with the molecular formula C8H8BrNO4, is a nitrobenzene derivative featuring a bromomethyl and a methoxy group. This chemical compound is utilized in organic synthesis and serves as a precursor for the creation of a variety of organic compounds. Its versatile properties position it as a valuable intermediate in the production of pharmaceuticals, dyes, and agrochemicals, making it an essential component in the chemical and pharmaceutical industries. However, due to its potential hazards to human health and the environment, careful handling is required.
Uses
Used in Organic Synthesis:
1-(BROMOMETHYL)-3-METHOXY-2-NITROBENZENE is used as a precursor in organic synthesis for the production of various organic compounds, leveraging its unique structure to facilitate the creation of a wide array of chemical products.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 1-(BROMOMETHYL)-3-METHOXY-2-NITROBENZENE is used as an intermediate in the manufacturing process of various pharmaceuticals. Its presence in the synthesis chain is crucial for the development of new drugs and medicines.
Used in Dye Production:
1-(BROMOMETHYL)-3-METHOXY-2-NITROBENZENE is used as a chemical intermediate in the production of dyes, contributing to the coloration and stability of these products in various applications.
Used in Agrochemicals:
1-(BROMOMETHYL)-3-METHOXY-2-NITROBENZENE is also utilized in the agrochemical sector, where it serves as an intermediate for the synthesis of various agrochemicals, playing a role in the development of products that protect and enhance crop yields.
Safety and Environmental Considerations:
Given its potential hazards, 1-(BROMOMETHYL)-3-METHOXY-2-NITROBENZENE must be handled with care to minimize risks to human health and the environment. Proper safety measures and disposal methods are essential to mitigate any adverse effects associated with its use.
Check Digit Verification of cas no
The CAS Registry Mumber 133486-62-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,3,4,8 and 6 respectively; the second part has 2 digits, 6 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 133486-62:
(8*1)+(7*3)+(6*3)+(5*4)+(4*8)+(3*6)+(2*6)+(1*2)=131
131 % 10 = 1
So 133486-62-1 is a valid CAS Registry Number.
133486-62-1Relevant articles and documents
Efficient synthesis of NIR emitting bis[2-(2′-hydroxylphenyl)benzoxazole] derivative and its potential for imaging applications
Wang, Junfeng,Baumann, Hannah,Bi, Xiaoman,Shriver, Leah P.,Zhang, Zhaoda,Pang, Yi
, (2020/01/25)
Unassymetric bis[2-(2′-hydroxyphenylbenzoxole)] bis(HBO) derivatives with a DPA functionality for zinc binding have been developed with an efficient synthetic route, using the retrosynthetic analysis. Comparison of bis(HBO) derivatives with different substitution patterns allows us to verify and optimize their unique fluorescence properties. Upon binding zinc cation, bis(HBO) derivatives give a large fluorescence turn-on in both visible (λem ≈ 536 nm) and near-infrared (NIR) window (λem ≈ 746 nm). The probes are readily excitable by a 488 nm laser, making this series of compounds a suitable imaging tool for in vitro and in vivo study on a confocal microscope. The application of zinc binding-induced fluorescence turn-on is successfully demonstrated in cellular environments and thrombus imaging.
CLASS OF NEAR INFRARED MOLECULAR PROBES FOR BIOLOGICAL APPLICATIONS
-
, (2014/10/16)
Methods for preparing 2,5-Bis(benzoxazol-2′-yl)benzene-1,4-diol derivatives (Zinhbo derivatives) are provided. Zinhbo derivatives are used to detect zinc ions and have particular application in vivo and in vitro. Zinhbo derivatives upon excitation give a florescence response emission that can be used to determine the presence of zinc cation in solution. Zinhbo derivatives complexed with zinc cations upon excitation can produce a florescence response emission in the visible and near infrared range. Zinhbo derivatives complexed with zinc cations exhibit a large stoke shift between the excitation and emission wavelengths.
Discovery of novel phosphonic acid derivatives as new chemical leads for inhibitors of TNF-α production
Matsui, Toshiaki,Takahashi, Shinya,Matsunaga, Naoki,Nakamura, Kazunori,Omawari, Nagashige,Sakai, Masaru,Kamoshima, Wataru,Terai, Kouichiro,Ohno, Hiroyuki,Obata, Takaaki,Nakai, Hisao,Toda, Masaaki
, p. 3807 - 3815 (2007/10/03)
2-(Acylamino)benzylphosphonic acid 6 derived from an artificial substrate of sphingomyelinase was found to show inhibitory activity of TNF-α production. Structural optimization was started with the chemical modification of 6. The discovery of another chem
