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Benzenemethanamine, 2,4-dichloro-α-methyl-, (S)-, commonly known as l-methamphetamine, is a chemical compound with stereochemistry, S, and a molecular formula of C8H10Cl2N. It is a derivative of methamphetamine and acts as a central nervous system stimulant. Classified as a Schedule II controlled substance, it has a high potential for abuse and addiction due to its effects on neurotransmitters in the brain, increasing levels of dopamine and norepinephrine, which result in heightened alertness and euphoria.

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  • 133492-69-0 Structure
  • Basic information

    1. Product Name: Benzenemethanamine,2,4-dichloro-a-methyl-,(S)-
    2. Synonyms: Benzenemethanamine,2,4-dichloro-a-methyl-,(S)-;Benzenemethanamine, 2,4-dichloro-α-methyl-, (αS)-;4-dichloro-a-Methyl-;(S)-1-(2,4-Dichlorophenyl)ethylaMine;Benzenemethanamine,2,4-dichloro-a-methyl-,(aS)-
    3. CAS NO:133492-69-0
    4. Molecular Formula: C8H9Cl2N
    5. Molecular Weight: 190.07
    6. EINECS: N/A
    7. Product Categories: API intermediates
    8. Mol File: 133492-69-0.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 256.4±25.0 °C(Predicted)
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: 1.262±0.06 g/cm3(Predicted)
    6. Refractive Index: N/A
    7. Storage Temp.: 2-8°C
    8. Solubility: N/A
    9. PKA: 8.28±0.10(Predicted)
    10. CAS DataBase Reference: Benzenemethanamine,2,4-dichloro-a-methyl-,(S)-(CAS DataBase Reference)
    11. NIST Chemistry Reference: Benzenemethanamine,2,4-dichloro-a-methyl-,(S)-(133492-69-0)
    12. EPA Substance Registry System: Benzenemethanamine,2,4-dichloro-a-methyl-,(S)-(133492-69-0)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 133492-69-0(Hazardous Substances Data)

133492-69-0 Usage

Uses

Used in Pharmaceutical Industry:
Benzenemethanamine, 2,4-dichloro-α-methyl-, (S)is used as an active pharmaceutical ingredient for the treatment of attention deficit hyperactivity disorder (ADHD) and narcolepsy, due to its stimulant properties that help improve focus and alertness.
Used in Research and Development:
In the scientific community, Benzenemethanamine, 2,4-dichloro-α-methyl-, (S)is utilized in research studies to understand the mechanisms of action of central nervous system stimulants and their potential therapeutic applications.
Benzenemethanamine, 2,4-dichloro-α-methyl-, (S)is often found in the illegal manufacture of methamphetamine, a highly addictive and dangerous substance. Its abuse can lead to serious health risks, including addiction, overdose, and neurological damage.

Check Digit Verification of cas no

The CAS Registry Mumber 133492-69-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,3,4,9 and 2 respectively; the second part has 2 digits, 6 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 133492-69:
(8*1)+(7*3)+(6*3)+(5*4)+(4*9)+(3*2)+(2*6)+(1*9)=130
130 % 10 = 0
So 133492-69-0 is a valid CAS Registry Number.

133492-69-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name (1S)-1-(2,4-dichlorophenyl)ethanamine

1.2 Other means of identification

Product number -
Other names 2,6-dichlorophenylethylamine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:133492-69-0 SDS

133492-69-0Relevant articles and documents

COMPOSITIONS AND METHODS FOR CYCLOFRUCTANS AS SEPARATION AGENTS

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Page/Page column 45-49; 62, (2010/12/31)

The present invention relates to derivatized cyclofructan compounds, compositions comprising derivatized cyclofructan compounds, and methods of using compositions comprising derivatized cyclofructan compounds for chromatographic separations of chemical species, including enantiomers. Said compositions may comprise a solid support and/or polymers comprising derivatized cyclofructan compounds.

Optically active amines by enzyme-catalyzed kinetic resolution

Ditrich, Klaus

experimental part, p. 2283 - 2287 (2009/04/06)

Chiral amines are resolved by an enzyme-catalyzed kinetic resolution. Key steps are the selective acylation of one enantiomer with isopropyl methoxyacetate, separation of the resulting amide from the unreacted antipode, and finally amide hydrolysis. The p

Quinoxaline compounds

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Page/Page column 17, (2008/06/13)

Certain amidophenyl-sulfonylamino-quinoxaline compounds are CCK2 modulators useful in the treatment of CCK2 mediated diseases.

N-(α-alkylbenzylidene)-α-phenylalkylamine, its use and process for producing the same and process for producing intermediate therefor

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, (2008/06/13)

There is disclosed an N-(α-alkylbenzylidene)-α-phenylalkylamine represented by the general formula (1): STR1 wherein R1 represents a lower alkyl group, R2 represents a hydrogen atom, a halogen atom, a lower alkyl group or a lower alkoxy group and X represents a halogen atom or a lower alkoxy group, its use and a process for producing the same and processes for producing intermediates therefor.

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