89981-75-9

Basic information

• Product Name: 1-(2,4-DICHLORO-PHENYL)-ETHYLAMINE
• Synonyms: 2, 4-DICHLORO-A-PHENETHYLAMINE;2,4-DICHLORO-ALPHA-METHYLBENZYLAMINE;2,4-DICHLORO-ALPHA-PHENETHYLAMINE;1-(2',4'-DICHLOROPHENYL)ETHYLAMINE;1-(2,4-DICHLORO-PHENYL)-ETHYLAMINE;1-AMINO-1-(2,4-DICHLOROPHENYL)ETHANE;4-alpha-Aminoethyl-1.3-dichlorobenzene;1-(2,4-dichlorophenyl)ethanamine(SALTDATA: FREE)
• CAS NO: 89981-75-9
• Molecular Formula: C₈H₉Cl₂N
• Molecular Weight: 190.07
• Product Categories: Anilines, Amides & Amines;Chlorine Compounds
• Mol File: 89981-75-9.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 132 °C / 15mmHg
• Flash Point: 108.8 °C
• Appearance: /
• Density: 1.262 g/cm³
• Vapor Pressure: 0.0155mmHg at 25°C
• Refractive Index: 1.56
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• PKA: 8.28±0.10(Predicted)
• CAS DataBase Reference: 1-(2,4-DICHLORO-PHENYL)-ETHYLAMINE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2,4-DICHLORO-PHENYL)-ETHYLAMINE(89981-75-9)
• EPA Substance Registry System: 1-(2,4-DICHLORO-PHENYL)-ETHYLAMINE(89981-75-9)

Safety Data

• Hazard Codes: C,Xi
• Statements: 36/37/38-36
• Safety Statements: 36/37/39-26
• HazardClass: IRRITANT
• Hazardous Substances Data: 89981-75-9(Hazardous Substances Data)

Usage

General Description

1-(2,4-DICHLORO-PHENYL)-ETHYLAMINE, also known as 2,4-dichlorophenethylamine, is an organic compound with the chemical formula C8H10Cl2. It is a derivative of phenethylamine, a type of organic compound commonly found in nature. 1-(2,4-DICHLORO-PHENYL)-ETHYLAMINE is used in the synthesis of various pharmaceutical drugs and is also an important intermediate for the production of other chemical compounds. It is known for its potential use in medicinal applications, particularly in the development of drugs for the treatment of various neurological and psychiatric disorders. Due to its chemical properties and structure, 1-(2,4-DICHLORO-PHENYL)-ETHYLAMINE has attracted attention in the fields of medicinal chemistry and drug discovery for its potential therapeutic benefits.

InChI:InChI=1/C8H9Cl2N/c1-5(11)7-3-2-6(9)4-8(7)10/h2-5H,11H2,1H3/p+1/t5-/m0/s1

Upstream product

• 35588-60-4 p-chloro-(R,S)-1-phenylethylamine 

Downstream Products

• 1528751-77-0 C₁₃H₁₇Cl₂NO 
• 1441785-69-8 2-((R)-1-(2,4-dichlorophenyl)ethylamino)-4-(4-((R)-piperidine-2-carbonyl)piperazin-1-yl)benzonitrile 
• 1441793-56-1 (R)-t-butyl 2-(4-(4-cyano-3-((R)-1-(2,4-dichlorophenyl)ethylamino)phenyl)piperazine-1-carbonyl)piperidine-1-carboxylate 
• 1441793-51-6 (R)-2-(1-(2,4-dichlorophenyl)ethylamino)-4-(piperazin-1-yl)benzonitrile 
• 1441793-45-8 (R)-t-butyl 4-(4-cyano-3-(1-(2,4-dichlorophenyl)ethylamino)phenyl)piperazine-1-carboxylate 
• 1441793-39-0 (R)-4-bromo-2-(1-(2,4-dichlorophenyl)ethylamino)benzonitrile 
• 1441785-53-0 (4-(3-((R)-1-(2,4-dichlorophenyl)ethylamino)-4-fluorophenyl)piperazin-1-yl)((R)-piperidin-2-yl)methanone 
• 1441793-27-6 (R)-t-butyl 2-(4-(3-((R)-1-(2,4-dichlorophenyl)ethylamino)-4-fluorophenyl)piperazine-1-carbonyl)piperidine-1-carboxylate 
• 1441793-21-0 (R)-N-(1-(2,4-dichlorophenyl)ethyl)-2-fluoro-5-(piperazin-1-yl)aniline 
• 1441793-16-3 (R)-t-butyl 4-(3-(1-(2,4-dichlorophenyl)ethylamino)-4-fluorophenyl)piperazine-1-carboxylate 
• 1441785-42-7 (R)-(1-(4-chloro-3-(1-(2,4-dichlorophenyl)ethylamino)phenyl)piperidin-4-yl)(morpholino)methanone 
• 1441792-87-5 (R)-1-(4-chloro-3-(1-(2,4-dichlorophenyl)ethylamino)phenyl)piperidine-4-carboxylic acid 
• 1441792-81-9 (R)-ethyl 1-(4-chloro-3-(1-(2,4-dichlorophenyl)ethylamino)phenyl)piperidine-4-carboxylate 
• 1441785-38-1 (1R,3R)-3-(4-(4-chloro-3-((R)-1-(2,4-dichlorophenyl)ethyIamino)phenyl)piperidin-1-yl)cyclohexanecarboxamide 

Relevant articles and documents

Process for producing optically active 3,3,3-Trifluoro-2-Hydroxy-2-Methylpropionic acid, and salt thereof

There are disclosed are a diastereomer salt of formula (1): a process for producing the same, a process for producing optically active 3,3,3-trifluoro-2-hydroxy-2-methylpropionic acid of formula (2′): a novel optically active amine compound of formula (4): a novel optically active amine compound of formula (8): an imine compound of formula (7) or (11):

Process for racemization of optically active 1-phenylethylamine derivative

A process for racemization of an optically active 1-phenylethylamine derivative represented by formula (I): STR1 wherein R1 represents a phenyl group substituted at least at the ortho-position, which comprises reacting the optically active 1-phenylethylamine derivative (1) with an aldehyde compound represented by formula (2): where R2 represents an optionally substituted alkyl group or an optionally substituted phenyl group to form an optically active imine represented by formula (3): STR2 reacting the imine with an alkaline metal tert-alkoxide in an aprotic solvent, and then hydrolyzing the resultant racemic imine.