133500-07-9

Basic information

• Product Name: 4,4-Dimethyl-6-(2-oxobutanyl)cyclohex-2-en-1-on
• CAS NO: 133500-07-9
• Molecular Weight: 194.274
• Mol File: 133500-07-9.mol

Chemical Properties

• CAS DataBase Reference: 4,4-Dimethyl-6-(2-oxobutanyl)cyclohex-2-en-1-on(CAS DataBase Reference)
• NIST Chemistry Reference: 4,4-Dimethyl-6-(2-oxobutanyl)cyclohex-2-en-1-on(133500-07-9)
• EPA Substance Registry System: 4,4-Dimethyl-6-(2-oxobutanyl)cyclohex-2-en-1-on(133500-07-9)

Safety Data

• Hazardous Substances Data: 133500-07-9(Hazardous Substances Data)

Upstream product

• 1073-13-8 4,4-dimethylcyclohexenone 
• 69567-06-2 (N-methylanilino)prop-2-enenitrile 
• 75-03-6 ethyl iodide 

Relevant articles and documents

Tandem-Michael addition of 1-cyanoenamines to cyclohexenones. A new access to bicyclo[2.2.2]octanones

Bicyclo[2.2.2]octane-2,5-diones 5 are easily obtained via tandem Michael addition of 2-(N-methylanilino)acrylonitrile (2) with deprotonated cyclohexenones I. The reaction is highly anti-stereoselective with respect to substituents on C-4 and C-5 of the cyclohexenone and is blocked by disubstitution on C-4. 6-Acylbicyclo[2.2.2]octan-2-ones 25 are obtained by tandem Michael addition of deprotonated 2-(N-methylanilino)but-2-enonitrile (18) with cyclohexenone and subsequent protonation or alkylation. Both reactions gave lower yields or even failed with cyclopentenone and cycloheptenone.