133513-04-9Relevant academic research and scientific papers
Palladium-catalyzed cross-coupling reactions of brominated porphyrins with functionalized organomagnesium reagents: Direct preparation of functional-group-bearing free base porphyrins
Sugita, Noriaki,Tsuchiya, Ikumi,Takanami, Toshikatsu
, p. 483 - 511 (2016)
The direct preparation of free-base porphyrins possessing reactive functional groups such as esters, halides, amide, nitriles, and acetals is described. This method relies on a simple one-pot procedure that involves sequential palladium-catalyzed cross-coupling of brominated free-base porphyrins with functionalized aryl and alkenylmagnesium reagents, which are readily prepared by iodine-magnesium exchange of the corresponding organic iodides with the turbo Grignard reagent i-PrMgCl·LiCl, followed by demetallation of the resulting magnesium porphyrins under very mild conditions involving either a 1.2 M aqueous methanol solution of HCl or a 0.1 M methanol solution of citric acid at ambient temperature.
SYNTHESIS OF TETRAPHENYLPORPHINES WITH ACTIVE GROUPS IN THE PHENYL RINGS6. SYNTHESIS OF MONOSUBSTITUTED TETRAPHENYLPORPHINES BY DIAZOTIZATION
Syrbu, S. A.,Semeikin, A. S.,Berezin, B. D.
, p. 1255 - 1257 (2007/10/02)
Monoaminophenyltriphenylporphines are diazotized and then used to produce monohalosubstituted tetraphenylporphines.Isomeric mono(p-hydroxyphenylazo)phenyltriphenylporphines are synthesized by replacing the azo group of diazonium salts of monosubstituted porphines with phenol.
