1335284-38-2Relevant academic research and scientific papers
Cascade synthesis of indolizines and pyrrolo[1,2-a]pyrazines from 2-formyl-1-propargylpyrroles
Escalante, Carlos H.,Carmona-Hernández, Fernando A.,Hernández-López, Alberto,Martínez-Mora, Eder I.,Delgado, Francisco,Tamariz, Joaquín
, p. 396 - 409 (2022/01/20)
A straightforward synthesis of indolizines and pyrrolo[1,2-a]pyrazines was performed through a cascade condensation/cyclization/aromatization reaction of substituted 2-formyl-N-propargylpyrroles with active methylene compounds such as nitromethane, alkyl
Mechanistic Insights into the Reaction of N-Propargylated Pyrrole- and Indole-Carbaldehyde with Ammonia, Alkyl Amines, and Branched Amines: A Synthetic and Theoretical Investigation
Sari, Ozlem,Seybek, Ali Fatih,Kaya, Serdal,Menges, Nurettin,Erdem, Safiye Sag,Balci, Metin
, p. 5261 - 5274 (2019/03/17)
The reaction of pyrrole- and indole-carbaldehydes having a propargyl group attached to the nitrogen atom with various amines was studied. The reaction with ammonia formed pyrrolo[1,2-a]pyrazine and pyrazino[1,2-a]indole while the reaction with alkylamines
Synthesis of pyrrolo[1,2-a]pyrazines and pyrazino[1,2-a]indoles by Curtius reaction in Morita-Baylis-Hillman derivatives
Nayak, Maloy,Pandey, Garima,Batra, Sanjay
, p. 7563 - 7569 (2011/10/09)
Synthesis of substituted pyrrolo[1,2-a]pyrazines and pyrazino[1,2-a]indoles from the Morita-Baylis-Hillman derivatives of acrylates via saponification followed by Curtius reaction is described.
