133541-45-4

Usage

Uses

Used in Organic Synthesis:
4-bromo-2,5-difluorobenzonitrile is utilized as a key building block in organic synthesis for its ability to contribute to the formation of various complex organic molecules. Its presence in the synthesis process can lead to the creation of compounds with specific desired properties.
Used in Pharmaceutical Production:
In the pharmaceutical industry, 4-bromo-2,5-difluorobenzonitrile is employed as an intermediate in the synthesis of drugs. Its unique combination of bromine and fluorine atoms, along with the nitrile group, allows for the development of pharmaceuticals with targeted therapeutic effects.
Used in Agrochemical Production:
4-bromo-2,5-difluorobenzonitrile is also used in the production of agrochemicals, where it serves as a precursor to compounds that can be used in the development of pesticides, herbicides, and other agricultural products to enhance crop protection and yield.
Used in Research Applications:
In research settings, 4-bromo-2,5-difluorobenzonitrile is leveraged for its potential in the discovery and development of new chemical entities. Its unique structural features make it a candidate for exploration in various chemical and material science research projects, contributing to advancements in the field.

InChI:InChI=1S/C7H2BrF2N/c8-5-2-6(9)4(3-11)1-7(5)10/h1-2H

Upstream product

• 357405-75-5 4-bromo-2,5-difluorobenzaldehyde 
• 2950-43-8 hydroxylamine-O-sulfonic acid 
• 327-51-5 1,4-dibromo-2,5-difluorobenzene 
• 764648-42-2 4-bromo-2,5-difluorobenzamide 
• 123942-09-6 4-bromo-2,5-difluorobenzoic acid chloride 
• 28314-82-1 4-bromo-2,5-difluorobenzoic acid 

Downstream Products

• 357405-77-7 4-bromo-2-[[(1R)-3-chloro-1-phenylpropyl]oxy]-5-fluorobenzonitrile 
• 764648-61-5 2-(4-bromo-2,5-difluorophenyl)-4-chloro-6-methylpyrimidine 
• 764648-45-5 4-bromo-2,5-difluorobenzamidine 

Relevant academic research and scientific papers

4-AMINO-6-(4-SUBSTITUTED-PHENYL)-PICOLINATES AND 6-AMINO-2-(4-SUBSTITUTED-PHENYL)-PYRIMIDINE-4-CARBOXYLATES AND THEIR USE AS HERBICIDES

Provided herein are 4-amino-6-(4-substituted-phenyl)-picolinic acids and their derivatives, and 6-amino-2-(4-substituted-phenyl)-pyrimidine-4-carboxylic acids and their derivatives, compositions comprising the acids and their derivatives, and methods of use thereof as herbicides.

Discovery and biological evaluation of novel 4-amino-2-phenylpyrimidine derivatives as potent and orally active GPR119 agonists

Novel 4-amino-2-phenylpyrimidine derivatives were synthesized and evaluated as GPR119 agonists. Optimization of the substituents on the phenyl ring at the 2-position and the amino group at the 4-position led to the identification of 3,4-dihalogenated and

Novel use of phenylheteroakylamine derivatives

There is disclosed the use of a compound of formula (I) wherein R1, R2, X, Y, V, W and Z are as defined in the specification, and pharmaceutically acceptable salts, enantiomers or racemates thereof, in the manufacture of a medicament, for the treatment or prophylaxis of diseases or conditions in which inhibition of nitric oxide synthase activity is beneficial. Certain novel compounds of formula (Ia) and pharmaceutically acceptable salts thereof, and enantiomers and racemates thereof are disclosed; together with processes for their preparation, compositions containing them and their use in therapy. The compounds of formulae (I) and (Ia) are inhibitors of the enzyme nitric oxide synthase and are thereby particularly useful in the treatment or prophylaxis of inflammatory disease.