133563-36-7

Upstream product

• 89-99-6 2-fluorobenzylamine 
• 133563-35-6 4-<(2-fluorobenzyl)amino>-3-nitropyridine 
• 13091-23-1 4-chloro-3-nitropyridine 

Downstream Products

• 1025917-64-9 4-Chloro-1-(2-fluoro-benzyl)-1H-[1,2,3]triazolo[4,5-c]pyridine 

Relevant academic research and scientific papers

1-(Fluorobenzyl)-4-amino-1H-1,2,3-triazolo[4,5-c]pyridines: Synthesis and anticonvulsant activity

A series of (fluorobenzyl)triazolo[4,5-c]pyridines was synthesized and tested for activity against maximal electroshock-induced seizures in rodents. The most promising compound, 14 (BW 534U87), which is a carbon-nitrogen isoster of a purine anticonvulsant, has a profile in rodents that suggests 14 will be free of emesis and useful in the treatment of seizure disorders for which phenytoin is presently indicated.

Pharmaceutically active triazolopyridine compounds

This invention describes the preparation and use of anticonvulsant agents. In particular, triazolopyridine compounds are described which have utility in the treatment of epilepsy in mammals.