133566-53-7Relevant academic research and scientific papers
1-Acyl- and 1,2-dihydro-1H(acyl)deoxyvasicinones. Synthesis and chemical transformations
Shakhidoyatov,Barakat, Yasser,Levkovich,Abdullaev
, p. 429 - 436 (2007)
1-Acyl-and 1,2-dihydro-1H(methyl, acyl)deoxyvasicinones were synthesized. Their PMR and 13C NMR spectra were investigated. The chemical shifts and SSCC were determined. 1-Acyl derivatives were produced by acylation of 1,2-dihydrodeoxyvascinone
1-Acyldeoxyvasicinone salts as effective intermediate C- and N-acylating agents for alkaloids and amino acids
Shakhidoyatov,Genjemuratova,Oripov
, p. 718 - 723 (2008/02/08)
The reaction of deoxyvasicinone with acid chlorides of aliphatic (acetylbromide) and aromatic (benzoyl-, o-, p-methoxy-, p-nitrobenzoylchlorides) acids was studied. It was shown that 1-deoxyvasicinone salts were formed at room temperature; α-aroyloxymethylidenedeoxyvasicinones, in the presence of triethylamine at 80-85°C. It was found that acid chlorides cause 1-acyldeoxyvasicinone salts to transform into α-hydroxy-or α-aroyloxyarylidenedeoxyvasicinones, which indirectly confirmed their acylating properties. It was found that 1-acyldeoxyvasicinone salts were effective acylating agents for alkaloids (cytisine, 1,2-dihydrodeoxyvasicinone) and amino acids (glycine, β-alanine, α-aminobutyric acid) and can be used to acylate primary and secondary aliphatic and heterocyclic amines.
SYNTHESIS, METHYLATION, AND ACYLATION OF 1,2-DIHYDRODEOXYVASICINONES AND THEIR HOMOLOGS
Shakhidoyatov, Kh. N.,Belova, G. A.
, p. 561 - 564 (2007/10/02)
2,3-Trimethylene- and 2,3-pentamethylene-1,2,3,4-tetrahydro-4-quinazolones and their 6-methyl and 6-bromo derivatives have been obtained by the reduction of deoxyvasicinone and its 6-methyl and 6-bromo derivatives and also their seven-membered homologs at
