133586-86-4Relevant academic research and scientific papers
Synthesis of 1,3-xoathiolane-2-thiones by the reaction of steroidal oxiranes with carbon disulfide
Shamsuzzaman,Salim, Anwar
, p. 5705 - 5708 (2007/10/03)
The reaction of 5, 6α-epoxy-5α-cholestane (1), its 3β-acetoxy-(2) and 3β- chloro-(3) analogues with carbon disulfide in THF at room temperature in the presence of Li Br as catalyst afford selectively the corresponding 1,3-oxathiolane-2-thiones (steroidal cyclic cis-dithiocarbonates) (4-6) in high yields.
SYNTHESIS OF STEROIDAL OXATHIOLANE THIONES
Shafiullah,Shamsuzzaman,Pathak, Rajesh Kumar
, p. 701 - 704 (2007/10/02)
The reaction of 5,6α-oxido-5α-cholestane (1) with carbon disulfide in the presence of triethylamine at room temperature affords 5α-cholestano-1',3'-oxathiolane-2'-thione (5).Under similar reaction conditions, its 3β-hydroxy (2), 3β-acetoxy (3) and 3β-chloro (4) analogues give 3β-hydroxy-5α-cholestano-1',3'-oxathiolane-2'-thione (6), 3β-acetoxy-5α-cholestano-1',3'-oxathiolane-2'-thione (7), and 3β-chloro-5α-cholestano-1',3'-oxathiolane-2'-thione (8), respectively.The structures of these compounds have been established on t he basis of elemental analyses and the spectral values.
