133595-72-9

Usage

Uses

Used in Pharmaceutical Industry:
1-(4-Hydroxyphenyl)-1-propanone oxime is used as an intermediate in the synthesis of various pharmaceuticals and drugs. Its unique structure and reactivity make it a valuable component in the development of new medications and therapies.
Used in Organic Synthesis:
In the field of organic synthesis, 1-(4-Hydroxyphenyl)-1-propanone oxime is used as a key compound for creating a range of organic molecules. Its versatility in reactions allows for the production of diverse chemical products.
Used in Neurodegenerative Disease Treatment:
1-(4-Hydroxyphenyl)-1-propanone oxime is used as a potential neuroprotective agent for the treatment of neurodegenerative diseases such as Alzheimer's. Its antioxidant properties contribute to its potential therapeutic effects in protecting neurons and减缓神经退行性疾病的进展 (slowing down the progression of neurodegenerative diseases).
Used in Antioxidant Applications:
Due to its antioxidant properties, 1-(4-Hydroxyphenyl)-1-propanone oxime can be used in various applications where antioxidant activity is beneficial, such as in the food industry to extend shelf life, in the cosmetic industry to protect skin from oxidative stress, and in the chemical industry to prevent the oxidation of sensitive compounds during storage and processing.

Upstream product

• 70-70-2 4-hydroxypropiophenone 
• 27914-73-4 4-acetoxybenzoyl chloride 
• 79119-31-6 N, N-diethyl-4-hydroxybenzamide 

Downstream Products

• 1135288-77-5 1-(4-hydroxyphenyl)-propan-1-amine hydrochloride 
• 115617-88-4 dl-5-chloro-6-ethyl-4-(α-ethyl-4-hydroxybenzylamino)-pyrimidine 
• 85068-38-8 α-[RS]Ethyl-4-hydroxybenzylamine 

Relevant academic research and scientific papers

APPLICATIONS OF N6-SUBSTITUTED ADENOSINE DERIVATIVE AND N6-SUBSTITUTED ADENINE DERIVATIVE TO CALMING, HYPNOSES, CONVULSION RESISTANCE, EPILEPTIC RESISTANCE, PARKINSON DISEASE RESISTANCE, AND DEMENTIA PREVENTION AND TREATMENT

PROBLEM TO BE SOLVED: To prepare analgesics, hypnotic agents, anticonvulsant agents, antiepileptics, antiparkinson drugs, dementia prophylactics, and health care food. SOLUTION: The present invention relates to an N6-substituted adenosine derivative and an N6-substituted adenine derivative selected from the group consisting of specific compounds. The present invention also relates to a pharmaceutical composition at least comprising a therapeutically effective amount of the compounds and a pharmaceutically acceptable carrier. The invention further relates to the compounds used in preparation of analgesics, hypnotic agents, anticonvulsant agents, antiepileptics, antiparkinson drugs, dementia prophylactics, and health care food. COPYRIGHT: (C)2016,JPO&INPIT

NITROGENATED HETEROCYCLIC COMPOUND

The present invention provides a compound having a PDE2A selective inhibitory action, which is useful as an agent for the prophylaxis or treatment of schizophrenia, Alzheimer's disease and the like. The present invention is a compound represented by the formula (1): wherein each symbol is as described in the specification, or a salt thereof.

N6-SUBSTITUTED ADENOSINE DERIVATIVES AND N6-SUBSTITUTED ADENINE DERIVATIVES AND USES THEREOF

The present invention provides N6-substituted adenosine derivatives and N6-substituted adenine derivatives, manufacturing methods thereof, a pharmaceutical composition comprising the said compounds above, and uses of these compounds in manufacturing medicaments and health-care products for treating insomnia, convulsion, epilepsy, and Parkinson's diseases, and preventing and treating dementia.

N6-SUBSTITUTED ADENOSINE DERIVATIVES, N6-SUBSTITUTED ADENINE DERIVATIVES AND USES THEREOF

The present invention provides N6-substituted adenosine derivatives and N6-substituted adenine derivatives, manufacturing methods thereof, a pharmaceutical composition comprising the said compounds above, and uses of of these compounds in manufacturing medicaments and health-care products for treating insomnia, convulsion, epilepsy, and Parkinson's diseases, and preventing and treating dementia.

Synthesis of benzylaminopyrimidines and their fungicidal activities against wheat brown rust and barley powdery mildew

Members of a new class of fungicide containing benzyl-aminopyrimidine as a core structure were synthesized and their fungicidal potencies against wheat brown rust, Puccinia recondita, and barley powdery mildew, Erysiphe graminis, were assessed. Among these fungicides, N-(fluoroalkoxy or fluorophenoxybenzyl)-4-pyrimidinamines showed notable preventive activities. The potency of the new pyrimidines was increased when a difluoromethoxy or tetrafluorophenoxy group was introduced at the 4- or 3-position of the phenyl moiety and a methyl or ethyl group was introduced at the benzyl position. Structure-activity relationships are discussed.