133614-04-7

Basic information

• Product Name: 2-Propen-1-one,1-(3-pyridinyl)-(9CI)
• Synonyms: 2-Propen-1-one,1-(3-pyridinyl)-(9CI);1-(3-pyridinyl)-2-Propen-1-one
• CAS NO: 133614-04-7
• Molecular Formula: C₈H₇NO
• Molecular Weight: 133.14728
• Product Categories: PYRIDINE
• Mol File: 133614-04-7.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 229.7±22.0 °C(Predicted)
• Appearance: /
• Density: 1.058±0.06 g/cm3(Predicted)
• PKA: 2.98±0.10(Predicted)
• CAS DataBase Reference: 2-Propen-1-one,1-(3-pyridinyl)-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Propen-1-one,1-(3-pyridinyl)-(9CI)(133614-04-7)
• EPA Substance Registry System: 2-Propen-1-one,1-(3-pyridinyl)-(9CI)(133614-04-7)

Safety Data

• Hazardous Substances Data: 133614-04-7(Hazardous Substances Data)

Usage

General Description

2-Propen-1-one,1-(3-pyridinyl)-(9CI) is a chemical compound with the molecular formula C7H5NO. It is a yellow liquid with a pungent odor and is commonly used in the production of pharmaceuticals, pesticides, and other industrial products. 2-Propen-1-one,1-(3-pyridinyl)-(9CI) is also known for its use as a flavoring agent and fragrance in the food and beverage industry. It is important to handle this chemical with caution as it is considered to be toxic and may cause irritation to the skin, eyes, and respiratory system. Additionally, it is important to follow proper safety protocols when handling and storing this chemical.

Upstream product

• 144825-44-5 (+/-)-tert-butyl 1-(pyridin-3'-yl)prop-2-en-1-yl carbonate 
• 1570-48-5 1-(pyridin-3-yl)propan-1-one 
• 350-03-8 methyl-3-pyridylketone 
• 50-00-0 formaldehyd 
• 1826-67-1 vinyl magnesium bromide 
• 95091-91-1 N-methoxy-N-methylpyridine-3-carboxamide 

Downstream Products

• 1239469-77-2 C₂₇H₂₈N₂O₃ 
• 867215-90-5 3-(2-(3-(2,6-dichlorophenyl)isoxazol-5-yl)pyridin-4-ylamino)-1-(pyridin-3-yl)propan-1-one 

Relevant articles and documents

Synthesis of 4-Acylpyrazoles from Saturated Ketones and Hydrazones Featured with Multiple C(sp3)-H Bond Functionalization and C-C Bond Cleavage and Reorganization

In this paper, an efficient and convenient one-pot synthesis of diversely substituted 4-acylpyrazole derivatives via copper-catalyzed one-pot cascade reactions of saturated ketones with hydrazones is reported. Mechanistically, the formation of the title compounds involves the in situ formation of an enone intermediate through the dehydrogenation of a saturated ketone and the [2 + 3] cyclization of the enone with hydrazone followed by an aromatization-driven C-C bond cleavage and reorganization. To our knowledge, this is the first example in which the biologically and pharmaceutically important yet otherwise difficult-to-obtain 4-acylpyrazole derivatives are directly prepared from saturated ketones and hydrazones featured with multiple aliphatic C-H bond functionalization and C-C bond cleavage and reorganization. Compared with literature methods, this novel process has advantages such as simple and economical starting materials, a sustainable oxidant, excellent regioselectivity, and good efficiency.

Access to the nicotine system by application of a guanidine-catalyzed asymmetric Michael addition of diphenyliminoacetate with 3-pyridyl vinyl ketone

A guanidine-based chiral organocatalyst was successfully applied to the Michael addition of diphenyliminoacetate to pyridyl vinyl ketone as a key reaction for the construction of the nicotine system.

2,5-diaryl tetrahydrofurans and analogs thereof as PAF antagonists

The present invention is directed to a specifically substituted tetrahydrofuran of the formula (I) STR1 wherein Ar is a pyridyl, dimethoxy-pyridyl or a dimethoxy-pyrazinyl group, R4 is an alkylthio, alkylsulfinyl or alkylsulfonyl containing gro