133615-53-9

Basic information

• Product Name: Benzeneethanol, b-(3-butenylamino)-, (R)-
• CAS NO: 133615-53-9
• Molecular Formula: C12H17NO
• Molecular Weight: 191.273
• Mol File: 133615-53-9.mol

Chemical Properties

• CAS DataBase Reference: Benzeneethanol, b-(3-butenylamino)-, (R)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzeneethanol, b-(3-butenylamino)-, (R)-(133615-53-9)
• EPA Substance Registry System: Benzeneethanol, b-(3-butenylamino)-, (R)-(133615-53-9)

Safety Data

• Hazardous Substances Data: 133615-53-9(Hazardous Substances Data)

Upstream product

• 56613-80-0 D-2-phenylglycinol 
• 5162-44-7 1-bromo-4-butene 

Downstream Products

• 1358767-04-0 C₁₂H₁₉NO 
• 154472-03-4 (3R,8aR)-(-)-3-phenyl-2,3,5,6,7,8-hexahydro-2H-oxazolo[3,8-a]pyridine 
• 133615-47-1 N-(3-butenyl)-5-phenyl-3-phenylthio-2-trimethylsilyloxymorpholine 
• 139904-58-8 (2R,4S)-4-Phenylsulfanyl-piperidine-1,2-dicarboxylic acid 2-(2-chloro-2-phenyl-ethyl) ester 1-vinyl ester 
• 133615-52-8 (2R,4R)-4-Acetoxy-piperidine-1,2-dicarboxylic acid 2-(2-chloro-2-phenyl-ethyl) ester 1-vinyl ester 
• 139904-57-7 (2R,4S)-4-Bromo-piperidine-1,2-dicarboxylic acid 2-(2-chloro-2-phenyl-ethyl) ester 1-vinyl ester 
• 139904-67-9 (2R,5S,6R,8S)-5-trimethylsilyloxy-2-phenyl-8-phenylthio-4-oxa-1-azabicyclo<4.4.0>decane 
• 133615-59-5 (2R,6R,8S)-5-oxo-2-phenyl-8-phenylthio-4-oxa-1-azabicyclo<4.4.0>decane 
• 133615-56-2 (2R,6R,8S)-5-hydroxy-2-phenyl-8-phenylthio-4-oxa-1-azabicyclo<4.4.0>decane 
• 139904-54-4 (2R,6R,8R)-8-azido-5-oxo-2-phenyl-4-oxa-1-azabicyclo<4.4.0>decane 
• 133615-51-7 (2R,6R,8R)-8-azido-5-oxo-2-phenyl-4-oxa-1-azabicyclo<4.4.0>decane 
• 133615-50-6 (2R,6R,8R)-8-acetoxy-5-hydroxy-2-phenyl-4-oxa-1-azabicyclo<4.4.0>decane 
• 139904-53-3 (2R,6R,8S)-8-bromo-5-oxo-2-phenyl-4-oxa-1-azabicyclo<4.4.0>decane 
• 133615-49-3 (2S,6R,8S)-8-bromo-5-hydroxy-2-phenyl-4-oxa-1-azabicyclo<4.4.0>decane 

Relevant articles and documents

Dimethylamine adducts of allylic triorganoboranes as effective reagents for Petasis-type homoallylation of primary amines with formaldehyde

Dimethylamine adducts of triallyl-, triprenyl- and trans-cinnamyl(dipropyl)borane are effective reagents for mild homoallylation of primary amines with aqueous formaldehyde in MeOH without an inert atmosphere. A new concept is proposed for the explanation of the high stability of allylborane-amine adducts in aqueous MeOH.

Stereoselective multicomponent assembly of enantiopure oxazolopiperidines and -azepines

A multicomponent reaction (MCR) based on a cyclohydrocarbonylation (CHC) driven by hydroformylation was set up toward the efficient diastereoselective preparation of oxazolopiperidines (4a-e) and -azepines (7a-d). The bicyclic oxazolidines were obtained from chiral N-alkenylamino alcohols via transient cyclic iminium intermediates that underwent an intramolecular cyclization from the appendant oxygen. On the basis of a series of different experimental conditions, the diastereocontrol observed during the formation of the oxazolidines is best explained by the stereoelectronic effect induced by an A1,3-strain in a common cyclic iminium intermediate (A). This new sequence is suitable for diversity oriented syntheses, allowing the preparation of enantiopure (S)- and (R)-coniceine in five steps from commercially available material.

Asymmetric Synthesis of Pipecolic Acid Derivatives

Condensation of chiral N-homoallyl β-amino alcohols with glyoxal produces iminium ions which are cyclized with complete stereoselectivity.These substrates, whose reactivity is closely dependent on the substitution pattern of the ethylenic moiety, undergo