133617-15-9Relevant academic research and scientific papers
Enantiopure encaged Verkade's superbases: Synthesis, chiroptical properties, and use as chiral derivatizing agent
Yang, Jian,Chatelet, Bastien,Hérault, Damien,Dufaud, Véronique,Robert, Vincent,Grass, Stéphane,Lacour, Jér?me,Vanthuyne, Nicolas,Jean, Marion,Albalat, Muriel,Dutasta, Jean-Pierre,Martinez, Alexandre
, p. 139 - 146 (2020)
Verkade's superbases, entrapped in the cavity of enantiopure hemicryptophane cages, have been synthesized with enantiomeric excess (ee) superior to 98%. Their absolute configuration has been determined by using electronic circular dichroism (ECD) spectros
Esterification of Carboxylic Acids with Alcohols Using Benzenesulphonyl and Methanesulphonyl Chlorides
Dharmaratne, H. R. W.,Gunatilaka, A. A. Leslie,Sotheeswaran, S.
, p. 39 - 41 (2007/10/02)
The role of benzene- and methane-sulphonyl chlorides as coupling agents in the esterification of carboxylic acids with alcohols has been investigated.Hindered tertiary alcohols require initial conversion of the acid to the mixed acid-anhydride with benzenesulphonyl chloride.It is necessary to adjust molar ratios for esterification with secondary alcohols so that the intermediate formed is the symmetrical acid anhydride, since mixed acid-anhydrides also give the sulphonates of the alcohols wihich are difficult to separate from the esters.
