1336270-00-8

Basic information

• Product Name: C₁₀H₁₀ClF₂N
• Synonyms: C₁₀H₁₀ClF₂N
• CAS NO: 1336270-00-8
• Molecular Weight: 217.646
• Mol File: 1336270-00-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₁₀H₁₀ClF₂N(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₀H₁₀ClF₂N(1336270-00-8)
• EPA Substance Registry System: C₁₀H₁₀ClF₂N(1336270-00-8)

Safety Data

• Hazardous Substances Data: 1336270-00-8(Hazardous Substances Data)

Upstream product

• 1422510-33-5 (S)-N-((S)-1-(3-chloro-2,6-difluorophenyl)but-3-en-1-yl)-2-methylpropane-2-sulfmamide 
• 1422510-32-4 (S,E)-N-(3-chloro-2,6-difluorobenzylidene)-2-methylpropane-2-sulfinamide 
• 190011-87-1 1-(3-chloro-2,6-difluoro-phenyl)-carboxaldehyde 

Downstream Products

• 1422510-34-6 (S)-phenyl (1-(3-chloro-2,6-difluorophenyl)but-3-en-1-yl)carbamate 
• 1422510-31-3 (S)-phenyl (1-(3-chloro-2,6-difluorophenyl)-3-oxopropyl)carbamate 

Relevant articles and documents

CYCLIC P1 LINKERS AS FACTOR XIA INHIBITORS

The present invention provides compounds of Formula (Ia): or stereoisomers, tautomers, or pharmaceutically acceptable salts thereof, wherein all the variables are as defined herein. These compounds are selective factor XIa inhibitors or dual inhibitors of FXIa and plasma kallikrein. This invention also relates to pharmaceutical compositions comprising these compounds and methods of treating thromboembolic and/or inflammatory disorders using the same.