133628-29-2Relevant academic research and scientific papers
Orthogonality and compatibility between Tsc and Fmoc amino-protecting groups
Choi, Jin Seok,Kang, Hunhui,Jeong, Nakcheol,Han, Hogyu
, p. 2493 - 2503 (2007/10/03)
New deprotection conditions that provide a complete orthogonality between Tsc and Fmoc amino-protecting groups are described. The potential of these orthogonal deprotection conditions was then demonstrated by the efficient solid-phase synthesis of branched peptides 20 and 21 using doubly protected amino acids such as Tsc-Lys(Fmoc)-OH 4c and Fmoc-Lys(Tsc)-OH 4d.
