133643-25-1Relevant academic research and scientific papers
CHIRAL AMINAL TEMPLATES 6. DIASTEREOSELECTIVITY OF HYDRAZONE ALKYLATION. ASYMMETRIC SYNTHESIS OF α-AMINOALDEHYDES
Alexakis, Alexandre,Lensen, Nathalie,Mangeney, Pierre
, p. 1171 - 1174 (1991)
Glyoxal is efficiently transformed into the chiral aminals bearing the hydrazone functionality 2a and 2b.These compounds react under complete diastereocontrol with various organolithium reagents, affording chiral hydrazines 3-9.Reduction with Raney nickel
