133646-35-2Relevant academic research and scientific papers
Total Synthesis of Hygromycin A
Chida, Noritaka,Ohtsuka, Masami,Nakazawa, Keiichi,Ogawa, Seiichiro
, p. 436 - 438 (1989)
The first complete synthesis of antibiotic hygromycin A is reported; coupling of the protected sugar moiety (2) and the aminocyclitol (3) derived from D-glucose as the optically active form, followed by deprotection, gives the product (1) which was identi
Total Synthesis of Antibiotic Hygromycin A
Chida, Noritaka,Ohtsuka, Masami,Nakazawa, Keiichi,Ogawa, Seiichiro
, p. 2976 - 2983 (2007/10/02)
The first total synthesis of the antibiotic (-)-hygromycin A (1) has been achieved by a coupling reaction of the sugar moiety (2) and the cyclitol moiety (3).Both components were synthesized in homochiral forms starting from D-glucose.This synthesis fully
